Alterations in thyroid hormone levels are well known to influence key functions in growth and development. Although in many countries the diet is fortified with iodide, essential for thyroid hormone synthesis, still not all humans have access to fortified diets, leaving a substantial part of the population at risk of developing hypothyroidism. To study the effects of thyroid hormones on testicular development, and Leydig cell development in particular, we prenatally induced hyper- and hypothyroidism in rats and studied Leydig cell development from the neonate up to adulthood. Earlier studies, using 6-propyl-2-thiouracil or high doses of tri-iodothyronine, were discontinued before puberty due to side effects. We used a different approach to ...
In this study we show that 6-propyl-2-thiouracil (PTU) treatment of Wistar rats from birth up to day...
The effects of propyl thiouracil (PTU)-induced hypothyroid-ism on testicular interstitial cells and ...
Background: Up until now, the effect of thyroid hormones on the male reproductive organ, after puber...
Alterations in thyroid hormone levels are well known to influence key functions in growth and develo...
Transient hypothyroidism induced by propyl-2-thiouracyl blocks postpartum Leydig cell development. I...
Transient neonatal 6-propyl-2-thiouracil (PTU) induced hypothyroidism affects Leydig and Sertoli cel...
Chronic prenatally induced dietary hypothyroidism delays adult-type Leydig cell development, but doe...
The objective of this study was to determine whether dietary-induced mild fetal/neonatal hyperthyroi...
Transient neonatal hypothyroidism in the rat causes prolonged Sertoli cell proliferation, delayed Se...
We tested the effects of thyroid hormone on Leydig cell (LC) regeneration in the adult rat testis af...
Transient neonatal 6-propyl-2-thiouracil (PTU) induced hypothyroidism affects Leydig and Sertoli cel...
License, which permits unrestricted use, distribution, and reproduction in any medium, provided the ...
By means of in vivo and in vitro approaches, we studied the effect of thyroid hormone on postnatal d...
Thyroid hormone is known to play a critical role in growth and development of rat testes with a spec...
Thyroid hormones are involved in the development of several tissues and organs and are essential for...
In this study we show that 6-propyl-2-thiouracil (PTU) treatment of Wistar rats from birth up to day...
The effects of propyl thiouracil (PTU)-induced hypothyroid-ism on testicular interstitial cells and ...
Background: Up until now, the effect of thyroid hormones on the male reproductive organ, after puber...
Alterations in thyroid hormone levels are well known to influence key functions in growth and develo...
Transient hypothyroidism induced by propyl-2-thiouracyl blocks postpartum Leydig cell development. I...
Transient neonatal 6-propyl-2-thiouracil (PTU) induced hypothyroidism affects Leydig and Sertoli cel...
Chronic prenatally induced dietary hypothyroidism delays adult-type Leydig cell development, but doe...
The objective of this study was to determine whether dietary-induced mild fetal/neonatal hyperthyroi...
Transient neonatal hypothyroidism in the rat causes prolonged Sertoli cell proliferation, delayed Se...
We tested the effects of thyroid hormone on Leydig cell (LC) regeneration in the adult rat testis af...
Transient neonatal 6-propyl-2-thiouracil (PTU) induced hypothyroidism affects Leydig and Sertoli cel...
License, which permits unrestricted use, distribution, and reproduction in any medium, provided the ...
By means of in vivo and in vitro approaches, we studied the effect of thyroid hormone on postnatal d...
Thyroid hormone is known to play a critical role in growth and development of rat testes with a spec...
Thyroid hormones are involved in the development of several tissues and organs and are essential for...
In this study we show that 6-propyl-2-thiouracil (PTU) treatment of Wistar rats from birth up to day...
The effects of propyl thiouracil (PTU)-induced hypothyroid-ism on testicular interstitial cells and ...
Background: Up until now, the effect of thyroid hormones on the male reproductive organ, after puber...