Summary Consumption of foods containing flavonoids is associated with a reduced risk of cardiovascular diseases (CVD), possibly by lipid-lowering effects. On the other hand, for one of these flavonoids, quercetin, also genotoxicity was shown especially in in vitro bioassays. Therefore, the first aim of this thesis was to identify mechanisms underlying potential beneficial health effects of flavonoids. The focus was on hepatic lipid metabolism and circulating lipids and a molecular and physiological approach was used. Secondly, we aimed to study the potential in vivo genotoxic effects of quercetin by transcriptome analyses in liver and small intestine, since these represent the tissues of first contact exposed to relatively high levels upon ...
Flavonoids are polyphenolic compounds whose main dietary source are fruits and vegetables. Epidemiol...
Obesity and dyslipidemia are major risk factors for the development of cardiovascular diseases (CVD)...
Quercetin, a flavonoid present in many fruits and vegetables, exhibits beneficial effects toward abn...
<strong>Summary</strong> Consumption of foods containing flavonoids is associated with a reduced ris...
Dietary flavonoids may protect against cardiovascular diseases (CVD). Increased circulating lipid le...
Dietary flavonoids may protect against cardiovascular diseases (CVD). Increased circulating lipid le...
Elevated circulating lipid levels are known risk factors for cardiovascular diseases (CVD). In order...
Elevated circulating lipid levels are known risk factors for cardiovascular diseases (CVD). In order...
Elevated circulating lipid levels are known risk factors for cardiovascular diseases (CVD). In order...
Contains fulltext : 144818.pdf (publisher's version ) (Open Access)Elevated circul...
Given the positive results of quercetin in in vitro genotoxicity studies, it is of interest to test ...
Given the positive results of quercetin in in vitro genotoxicity studies, the in vivo genotoxic prop...
Dietary flavonoid intake is associated with reduced risk of cardiovascular diseases, possibly by aff...
Flavonoids are polyphenolic compounds that occur ubiquitously in foods of plant origin. Over 4,000 d...
Flavonoids are polyphenolic compounds that occur ubiquitously in foods of plant origin. Over 4000 di...
Flavonoids are polyphenolic compounds whose main dietary source are fruits and vegetables. Epidemiol...
Obesity and dyslipidemia are major risk factors for the development of cardiovascular diseases (CVD)...
Quercetin, a flavonoid present in many fruits and vegetables, exhibits beneficial effects toward abn...
<strong>Summary</strong> Consumption of foods containing flavonoids is associated with a reduced ris...
Dietary flavonoids may protect against cardiovascular diseases (CVD). Increased circulating lipid le...
Dietary flavonoids may protect against cardiovascular diseases (CVD). Increased circulating lipid le...
Elevated circulating lipid levels are known risk factors for cardiovascular diseases (CVD). In order...
Elevated circulating lipid levels are known risk factors for cardiovascular diseases (CVD). In order...
Elevated circulating lipid levels are known risk factors for cardiovascular diseases (CVD). In order...
Contains fulltext : 144818.pdf (publisher's version ) (Open Access)Elevated circul...
Given the positive results of quercetin in in vitro genotoxicity studies, it is of interest to test ...
Given the positive results of quercetin in in vitro genotoxicity studies, the in vivo genotoxic prop...
Dietary flavonoid intake is associated with reduced risk of cardiovascular diseases, possibly by aff...
Flavonoids are polyphenolic compounds that occur ubiquitously in foods of plant origin. Over 4,000 d...
Flavonoids are polyphenolic compounds that occur ubiquitously in foods of plant origin. Over 4000 di...
Flavonoids are polyphenolic compounds whose main dietary source are fruits and vegetables. Epidemiol...
Obesity and dyslipidemia are major risk factors for the development of cardiovascular diseases (CVD)...
Quercetin, a flavonoid present in many fruits and vegetables, exhibits beneficial effects toward abn...