Add to ORKGWe recently reported that a sequence variant in the cell-cycle-checkpoint kinase CHEK2 (CHEK2 1100delC) is a low-penetrance breast cancer-susceptibility allele in noncarriers of BRCA1 or BRCA2 mutations. To investigate whether other CHEK2 variants confer susceptibility to breast cancer, we screened the full CHEK2 coding sequence in BRCA1/2-negative breast cancer cases from 89 pedigrees with three or more cases of breast cancer. We identified one novel germline variant, R117G, in two separate families. To evaluate the possible association of R117G and two germline variants repo
Mutations in BRCA1 and BRCA2 confer a high risk of breast and ovarian cancer1, but account for only ...
CHEK2 (previously known as “CHK2”) is a cell-cycle–checkpoint kinase that phosphorylates p53 and BRC...
Cell cycle checkpoint kinase 2 (CHEK2) is a transducer of cellular responses to DNA damage. The CHEK...
textabstractWe recently reported that a sequence variant in the cell-cycle-c...
We recently reported that a sequence variant in the cell-cycle–checkpoint kinase CHEK2 (CHEK2 1100de...
We recently reported that a sequence variant in the cell-cycle–checkpoint kinase CHEK2 (CHEK2 1100de...
We recently reported that a sequence variant in the cell-cycle-checkpoint ki...
The frame-shifting mutation 1100delC in the cell-cycle-checkpoint kinase 2 gene (CHEK2) has been rep...
The frame-shifting mutation 1100delC in the cell-cycle-checkpoint kinase 2 gene (CHEK2) has been rep...
The frame-shifting mutation 1100delC in the cell-cycle-checkpoint kinase 2 gene (CHEK2) has been rep...
The frame-shifting mutation 1100delC in the cell-cycle-checkpoint kinase 2 gene (CHEK2) has been rep...
The frame-shifting mutation 1100delC in the cell-cycle-checkpoint kinase 2 gene (CHEK2) has been rep...
The frame-shifting mutation 1100delC in the cell-cycle-checkpoint kinase 2 gene (CHEK2) has been rep...
The frame-shifting mutation 1100delC in the cell-cycle-checkpoint kinase 2 gene (CHEK2) has been rep...
Mutations in BRCA1 and BRCA2 confer a high risk of breast and ovarian cancer, but account for only a...
Mutations in BRCA1 and BRCA2 confer a high risk of breast and ovarian cancer1, but account for only ...
CHEK2 (previously known as “CHK2”) is a cell-cycle–checkpoint kinase that phosphorylates p53 and BRC...
Cell cycle checkpoint kinase 2 (CHEK2) is a transducer of cellular responses to DNA damage. The CHEK...
textabstractWe recently reported that a sequence variant in the cell-cycle-c...
We recently reported that a sequence variant in the cell-cycle–checkpoint kinase CHEK2 (CHEK2 1100de...
We recently reported that a sequence variant in the cell-cycle–checkpoint kinase CHEK2 (CHEK2 1100de...
We recently reported that a sequence variant in the cell-cycle-checkpoint ki...
The frame-shifting mutation 1100delC in the cell-cycle-checkpoint kinase 2 gene (CHEK2) has been rep...
The frame-shifting mutation 1100delC in the cell-cycle-checkpoint kinase 2 gene (CHEK2) has been rep...
The frame-shifting mutation 1100delC in the cell-cycle-checkpoint kinase 2 gene (CHEK2) has been rep...
The frame-shifting mutation 1100delC in the cell-cycle-checkpoint kinase 2 gene (CHEK2) has been rep...
The frame-shifting mutation 1100delC in the cell-cycle-checkpoint kinase 2 gene (CHEK2) has been rep...
The frame-shifting mutation 1100delC in the cell-cycle-checkpoint kinase 2 gene (CHEK2) has been rep...
The frame-shifting mutation 1100delC in the cell-cycle-checkpoint kinase 2 gene (CHEK2) has been rep...
Mutations in BRCA1 and BRCA2 confer a high risk of breast and ovarian cancer, but account for only a...
Mutations in BRCA1 and BRCA2 confer a high risk of breast and ovarian cancer1, but account for only ...
CHEK2 (previously known as “CHK2”) is a cell-cycle–checkpoint kinase that phosphorylates p53 and BRC...
Cell cycle checkpoint kinase 2 (CHEK2) is a transducer of cellular responses to DNA damage. The CHEK...