Lower incidence rates but thicker melanomas in Eastern Europe before 1992: A comparison with Western Europe
- Vries, Elisabeth
- Boniol, Mathieu
- Doré, J.F.
- Coebergh, Jan Willem
- Aareleid, T.
- Grosclaude, P.
- Ziegler, H.
- Berrino, Franco
- Allemani, Claudia
- Baili, Paolo
- Ciccolallo, L.
- Crosignani, P.
- Gatta, Gemma
- Micheli, A.
- Sant, Milena
- Taussig, E.
- Zanetti, Roberto
- Paci, Eugenio
- Crocetti, Emanuele
- Capocaccia, Riccardo
- Carrani, Eugenio
- Angelis, R.
- Roazzi, P.
- Santaquilani, Mariano
- Tavilla, A.
- Valente, José
- Verdecchia, A.
- Rachtan, J.
- Bielska-Lasota, Magdalena
- Wronkowski, Z.
- Pleško, I.
- Pompe-Kirn, V.
- Martinez-Garcia, Carmen
- Möller, Thomas
- Lutz, J.
- Godward, S.
- Forman, David
- Quinn, M.
- Roche, M.
- Edwards, S.
- Smith, Jeremy
- Lawrence, G.
DOIAbstract
The objective of this study was to investigate the epidemiology of melanoma across Europe with regard to Breslow thickness and body-site distribution. Incidence data from Cancer Incidence in 5 Continents and the EUROCARE-melanoma database were used: 28 117 melanoma cases from 20 cancer registries in 12 European countries, diagnosed between 1978 and 1992. Regression analysis and general linear modelling were used to analyse the data. Melanomas in Eastern Europe were on average 1.4 mm thicker (P<0.05) than in Western Europe and appeared more often on the trunk. From 1978 to 1992, their Breslow thickness had decreased in Western but not Eastern Europe. There was a latitude gradient in incidence, with highest rates in southern regions in Easter...
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