It is assumed that accreting neutron stars in low-mass X-ray binaries are heated due to the compression of the existing crust by the freshly accreted matter which gives rise to a variety of nuclear reactions in the crust. It has been shown that most of the energy is released deep in the crust by pycnonuclear reactions involving low-Z elements (the deep-crustal heating scenario). In this paper we discuss if neutron stars in the so-called very-faint X-ray transients (VFXTs; those transients have outburst peak 2-10 keV X-ray luminosities <1 × 1036 erg s−1) can be used to test this deep-crustal heating model. We demonstrate that such systems would indeed be very interesting objects to test the deep-crustal heating model with, but that the inter...