Towards a genetic AIDS vaccine

ABSTRACT: We discuss a recent Nature Medicine publication by Philip Johnson and co-workers (Vector-mediated gene transfer engenders long-lived neutralizing activity and protection against SIV infection in monkeys. Nat.Med. 2009, 15: 901-906) in which an effective HIV-1 vaccine is designed that is based on a gene therapy. The introduced gene produces an antibody-like immunoadhesin in the blood that neutralizes the viru