This study presents an integrated energy and emission management strategy which minimizes the operational costs over the study test cycle. This Integrated Powertrain Control (IPC) strategy deals with high system complexity and exploits the synergy between engine-aftertreatment systems by following a model-based approach. The potential of this integrated approach is demonstrated for a new application: an Euro-VI diesel engine with Waste Heat Recovery system. Main contribution of this work is to include the emission constraints in the control design for this application. In a simulation study, the performance of the presented IPC strategy is compared with a baseline engine control strategy over the World Harmonized Transient Cycle. It is show...