BACKGROUND: We developed and tested a simple dosing strategy for rapid induction with isoflurane followed by maintenance under minimal-flow conditions, that is 0.5 litre min(-1) total fresh gas flow (FGF). An end-expired concentration was to be achieved within 5 min in a desired therapeutic window, that is 0.8-1.1 vol%, and to be maintained within it for at least 30 min. METHODS: With our new model we computed a three-stage regimen using one fixed vaporizer setting: 3 vol% isoflurane in a FGF of 3 and 1.5 litre min(-1), each for 3 min, and 0.5 litre min thereafter. The ratio of nitrous oxide:oxygen was, consecutively, 2:1, 2:1, and 2:3. We evaluated this scheme in 58 adult patients (body mass 74 (SD 13) kg), mostly during eye and ear, nose,...
Background: In general anaesthesia practice a fresh gas flow (FGF) of ≥0.5 L/min is usually applied....
Abstract Background: Isocapnic hyperventilation (IHV) has been shown to shorten recovery time after ...
We studied the clinical use of an automatic feedback control system to adjust the end‐tidal anaesthe...
Item does not contain fulltextBACKGROUND: We developed and tested a simple dosing strategy for rapid...
Item does not contain fulltextWe explored our model by displaying its new capabilities, testing its ...
Item does not contain fulltextBACKGROUND: We quantified the predictive performance of our computer m...
Item does not contain fulltextThis paper is the first of a series of reports on a system model for t...
BACKGROUND: The Anesthetic Conserving Device (AnaConDa) uncouples delivery of a volatile anestheti...
Background: The wide range of fresh gas flow - vaporizer setting (FGF - FD) combinations used by dif...
Background. We propose a 1-1-12 wash-in scheme for desflurane-nitrous oxide (N2O) low-flow anesthesi...
BACKGROUND: The disposition of inhalation anaesthetics is governed by the factors described in the F...
Objective: To determine the effects of nitrous oxide (N2O) on the speed and quality of the uptake pr...
Contains fulltext : 51677.pdf (publisher's version ) (Closed access)Pharmacokineti...
The induction characteristics of sevoflurane in nitrous oxide and oxygen were compared with sevoflur...
The usual method of inhalation induction of anaesthesia is to administer a low concentration of an a...
Background: In general anaesthesia practice a fresh gas flow (FGF) of ≥0.5 L/min is usually applied....
Abstract Background: Isocapnic hyperventilation (IHV) has been shown to shorten recovery time after ...
We studied the clinical use of an automatic feedback control system to adjust the end‐tidal anaesthe...
Item does not contain fulltextBACKGROUND: We developed and tested a simple dosing strategy for rapid...
Item does not contain fulltextWe explored our model by displaying its new capabilities, testing its ...
Item does not contain fulltextBACKGROUND: We quantified the predictive performance of our computer m...
Item does not contain fulltextThis paper is the first of a series of reports on a system model for t...
BACKGROUND: The Anesthetic Conserving Device (AnaConDa) uncouples delivery of a volatile anestheti...
Background: The wide range of fresh gas flow - vaporizer setting (FGF - FD) combinations used by dif...
Background. We propose a 1-1-12 wash-in scheme for desflurane-nitrous oxide (N2O) low-flow anesthesi...
BACKGROUND: The disposition of inhalation anaesthetics is governed by the factors described in the F...
Objective: To determine the effects of nitrous oxide (N2O) on the speed and quality of the uptake pr...
Contains fulltext : 51677.pdf (publisher's version ) (Closed access)Pharmacokineti...
The induction characteristics of sevoflurane in nitrous oxide and oxygen were compared with sevoflur...
The usual method of inhalation induction of anaesthesia is to administer a low concentration of an a...
Background: In general anaesthesia practice a fresh gas flow (FGF) of ≥0.5 L/min is usually applied....
Abstract Background: Isocapnic hyperventilation (IHV) has been shown to shorten recovery time after ...
We studied the clinical use of an automatic feedback control system to adjust the end‐tidal anaesthe...