OBJECTIVE: To investigate the role of endotoxin-induced inflammatory mediators in blood on the permeability of endothelial monolayers. DESIGN: Whole blood of healthy volunteers was treated with bacterial lipopolysaccharide (Escherichia coli, B55:05), and the resultant plasma was added to human umbilical venular endothelial cells (HUVEC) cultured on semipermeable membrane inserts (Transwells). SETTING: University hospital laboratory. SUBJECTS: Whole blood of healthy volunteers. INTERVENTIONS: Donor plasma was treated with excess antibodies against either tumor necrosis factor-alpha, interleukin-1beta, or both, before the incubation on HUVEC. MEASUREMENTS AND MAIN RESULTS: The permeability of HUVEC monolayers to fluorescent-labeled albumin an...
Contains fulltext : 87263.pdf (publisher's version ) (Closed access)A widely appli...
Contains fulltext : 80340.pdf (publisher's version ) (Closed access)OBJECTIVE: End...
The endothelium controls the influx of macromolecules into the tissues, a process that may be distur...
Contains fulltext : 51276.pdf (publisher's version ) (Closed access)The aim of thi...
The aim of this study was to elucidate the time course of the permeability response of endothelial m...
Contains fulltext : 47937.pdf (publisher's version ) (Closed access)AIM: To invest...
AIM: To investigate whether the inflammatory response of cultured endothelial cells, as induced by c...
Contains fulltext : 57347.pdf (publisher's version ) (Closed access)The relative c...
Contains fulltext : 48813.pdf ( ) (Open Access)INTRODUCTION: Septic shock is assoc...
INTRODUCTION: Septic shock is associated with increased microvascular permeability. As a model for s...
Monolayer cultures of human umbilical vein endothelial cells were established and tested for the eff...
BACKGROUND AND OBJECTIVE: Vascular fibrinolysis, a major natural defense mechanism against thrombosi...
International audienceObjectives: Sepsis is defined as the host's inflammatory response to a lifethr...
OBJECTIVE: Endotoxin (lipopolysaccharide [LPS]) tolerance is characterized by a reduced responsivene...
Inflammation is the immediate response to tissue damage or harmful stimuli. Though inconvenient, its...
Contains fulltext : 87263.pdf (publisher's version ) (Closed access)A widely appli...
Contains fulltext : 80340.pdf (publisher's version ) (Closed access)OBJECTIVE: End...
The endothelium controls the influx of macromolecules into the tissues, a process that may be distur...
Contains fulltext : 51276.pdf (publisher's version ) (Closed access)The aim of thi...
The aim of this study was to elucidate the time course of the permeability response of endothelial m...
Contains fulltext : 47937.pdf (publisher's version ) (Closed access)AIM: To invest...
AIM: To investigate whether the inflammatory response of cultured endothelial cells, as induced by c...
Contains fulltext : 57347.pdf (publisher's version ) (Closed access)The relative c...
Contains fulltext : 48813.pdf ( ) (Open Access)INTRODUCTION: Septic shock is assoc...
INTRODUCTION: Septic shock is associated with increased microvascular permeability. As a model for s...
Monolayer cultures of human umbilical vein endothelial cells were established and tested for the eff...
BACKGROUND AND OBJECTIVE: Vascular fibrinolysis, a major natural defense mechanism against thrombosi...
International audienceObjectives: Sepsis is defined as the host's inflammatory response to a lifethr...
OBJECTIVE: Endotoxin (lipopolysaccharide [LPS]) tolerance is characterized by a reduced responsivene...
Inflammation is the immediate response to tissue damage or harmful stimuli. Though inconvenient, its...
Contains fulltext : 87263.pdf (publisher's version ) (Closed access)A widely appli...
Contains fulltext : 80340.pdf (publisher's version ) (Closed access)OBJECTIVE: End...
The endothelium controls the influx of macromolecules into the tissues, a process that may be distur...