Increased availability of fatty acids released from insulin-resistant adipose tissue may lead to excess fatty acid uptake in nonadipose organs, including the heart. Accumulation of toxic fatty acid intermediates may affect cardiac function. Our aim was to identify to which extent high-fat diet feeding leads to alterations in cardiac function and whether this depends on gender and (or) duration of high-fat diet feeding. Male and female C57Bl/6J mice (n = 8 per group) of 12 to 16 weeks old were fed a low-fat (10% energy) or high-fat (45% energy) lard diet for 6 or 12 weeks. Plasma lipid levels, echocardiography, and left ventricular pressure-volume relationships were obtained at 2, 1, and 0 weeks before termination, respectively. In both male...
AbstractVariations in the fatty acid composition of lipids in the heart alter its function and susce...
Background/Aims: Altered nutrients during the in utero (IU) and/or lactation (L) period predispose...
OBJECTIVE: Parental high-fat feeding was proposed to negatively impact metabolic health in offspring...
Increased availability of fatty acids released from insulin-resistant adipose tissue may lead to exc...
Item does not contain fulltextIncreased availability of fatty acids released from insulin-resistant ...
Preclinical studies of animals with risk factors, and how those risk factors contribute to the devel...
PURPOSE: High calorie intake leads to obesity, a global socio-economic and health problem, reaching ...
International audienceBackground: Western diet, rich in saturated fatty acids and cholester...
Obesity is related with cardiac hypertrophy, or the enlargement of the heart, due to the increased d...
High fat, low carb diets are becoming increasingly popular in the United States as part of new weigh...
Background Metabolic syndrome (MetS) refers to a cluster of co-existing cardio-metabolic risk factor...
Normal myocardium adapts to increase of nutritional fatty acid supply by upregulation of regulatory ...
BACKGROUND: Excess body fat is a major health issue and a risk factor for the development of numerou...
It has been established that placing the C57BL6/J mouse on a high fat diet induces obesity and impa...
Variations in the fatty acid composition of lipids in the heart alter its function and susceptibilit...
AbstractVariations in the fatty acid composition of lipids in the heart alter its function and susce...
Background/Aims: Altered nutrients during the in utero (IU) and/or lactation (L) period predispose...
OBJECTIVE: Parental high-fat feeding was proposed to negatively impact metabolic health in offspring...
Increased availability of fatty acids released from insulin-resistant adipose tissue may lead to exc...
Item does not contain fulltextIncreased availability of fatty acids released from insulin-resistant ...
Preclinical studies of animals with risk factors, and how those risk factors contribute to the devel...
PURPOSE: High calorie intake leads to obesity, a global socio-economic and health problem, reaching ...
International audienceBackground: Western diet, rich in saturated fatty acids and cholester...
Obesity is related with cardiac hypertrophy, or the enlargement of the heart, due to the increased d...
High fat, low carb diets are becoming increasingly popular in the United States as part of new weigh...
Background Metabolic syndrome (MetS) refers to a cluster of co-existing cardio-metabolic risk factor...
Normal myocardium adapts to increase of nutritional fatty acid supply by upregulation of regulatory ...
BACKGROUND: Excess body fat is a major health issue and a risk factor for the development of numerou...
It has been established that placing the C57BL6/J mouse on a high fat diet induces obesity and impa...
Variations in the fatty acid composition of lipids in the heart alter its function and susceptibilit...
AbstractVariations in the fatty acid composition of lipids in the heart alter its function and susce...
Background/Aims: Altered nutrients during the in utero (IU) and/or lactation (L) period predispose...
OBJECTIVE: Parental high-fat feeding was proposed to negatively impact metabolic health in offspring...