Diffuse intrinsic pontine glioma (DIPG) is a fatal malignancy because of its diffuse infiltrative growth pattern. Translational research suffers from the lack of a representative DIPG animal model. Hence, human E98 glioma cells were stereotactically injected into the pons of nude mice. The E98 DIPG tumors presented a strikingly similar histhopathology to autopsy material of a DIPG patient, including diffuse and perivascular growth, brainstem- and supratentorial invasiveness and leptomeningeal growth. Magnetic resonance imaging (MRI) was effectively employed to image the E98 DIPG tumor. [(18) F] 3'-deoxy-3'-[(18) F]fluorothymidine (FLT) positron emission tomography (PET) imaging was applied to assess the subcutaneous (s.c.) E98 tumor prolife...
Background: CNS injury including stroke, infection, and tumor growth lead to astrogliosis, a process...
PURPOSE: To develop a transgenic mouse model of glioma that can be conveniently used for testing the...
Purpose: To develop a transgenic mouse model of glioma that can be conveniently used for testing the...
Item does not contain fulltextDiffuse intrinsic pontine glioma (DIPG) is a fatal malignancy because ...
Diffuse intrinsic pontine glioma (DIPG) is a rare and incurable brain tumor that arises in the brain...
Diffuse intrinsic pontine glioma (DIPG) is a rare and incurable brain tumor that arises predominatel...
Diffuse intrinsic pontine gliomas (DIPGs) represent a particularly lethal type of pediatric brain ca...
Diffuse intrinsic pontine glioma (DIPG) is a rare and incurable brain tumor that arises predominatel...
Diffuse intrinsic pontine glioma (DIPG), with a median survival of only 9 months, is the leading cau...
OBJECTIVE: To use in vivo imaging methods in mice to quantify intracranial glioma growth, to correla...
Diffuse intrinsic pontine gliomas (DIPGs) are incurable childhood brain tumors, whereby the standard...
AbstractDiffuse intrinsic pontine glioma (DIPG) is a rare and incurable brain tumor that arises pred...
<div><p>Diffuse intrinsic pontine gliomas (DIPGs) represent a particularly lethal type of pediatric ...
BackgroundDiffuse intrinsic pontine gliomas represent a unique subtype of primary brain tumors occur...
Simple Summary The creation of stable fluorescent glioma cell lines opens prospects for the detailed...
Background: CNS injury including stroke, infection, and tumor growth lead to astrogliosis, a process...
PURPOSE: To develop a transgenic mouse model of glioma that can be conveniently used for testing the...
Purpose: To develop a transgenic mouse model of glioma that can be conveniently used for testing the...
Item does not contain fulltextDiffuse intrinsic pontine glioma (DIPG) is a fatal malignancy because ...
Diffuse intrinsic pontine glioma (DIPG) is a rare and incurable brain tumor that arises in the brain...
Diffuse intrinsic pontine glioma (DIPG) is a rare and incurable brain tumor that arises predominatel...
Diffuse intrinsic pontine gliomas (DIPGs) represent a particularly lethal type of pediatric brain ca...
Diffuse intrinsic pontine glioma (DIPG) is a rare and incurable brain tumor that arises predominatel...
Diffuse intrinsic pontine glioma (DIPG), with a median survival of only 9 months, is the leading cau...
OBJECTIVE: To use in vivo imaging methods in mice to quantify intracranial glioma growth, to correla...
Diffuse intrinsic pontine gliomas (DIPGs) are incurable childhood brain tumors, whereby the standard...
AbstractDiffuse intrinsic pontine glioma (DIPG) is a rare and incurable brain tumor that arises pred...
<div><p>Diffuse intrinsic pontine gliomas (DIPGs) represent a particularly lethal type of pediatric ...
BackgroundDiffuse intrinsic pontine gliomas represent a unique subtype of primary brain tumors occur...
Simple Summary The creation of stable fluorescent glioma cell lines opens prospects for the detailed...
Background: CNS injury including stroke, infection, and tumor growth lead to astrogliosis, a process...
PURPOSE: To develop a transgenic mouse model of glioma that can be conveniently used for testing the...
Purpose: To develop a transgenic mouse model of glioma that can be conveniently used for testing the...