Psoriasis is an autoimmune-related chronic inflammatory skin disease that is strongly associated with IL-23 and T helper-17 (Th17) effector cytokines. In addition, CD4+CD25(high) regulatory T-cell (Treg) function appeared to be impaired in psoriasis. CD4+CD25(high)Foxp3+ Tregs are typically considered inhibitors of autoimmune responses. However, under proinflammatory conditions, Tregs can differentiate into inflammation-associated Th17 cells--a paradigm shift, with as yet largely unknown consequences for human disease initiation or progression. Th17 cells are highly proinflammatory T cells that are characterized by IL-17A and IL-22 production and expression of the transcription factor retinoic acid-related orphan receptor gammat (RORgammat)...
Abnormal production of inflammatory mediators is believed to play an important role in the pathogene...
Psoriasis is a chronic inflammatory disease mediated by a complex interplay between immune system an...
BACKGROUND: In the pathogenesis of psoriasis, proinflammatory T cells are strongly involved in the i...
Psoriasis is an autoimmune-related chronic inflammatory skin disease that is strongly associated wit...
Contains fulltext : 96935.pdf (publisher's version ) (Closed access)Psoriasis is a...
Psoriasis is one of the most common inflammatory skin conditions affecting both children and adults....
Psoriasis is a chronic inflammatory skin disease characterized by accelerated tumor necrosis factor-...
Psoriasis is a hereditary disease elicited by chronic activation of cutaneous T cells. Delineating t...
Regulatory T cells (Tregs) are crucial controllers of inflammation. Patients with a genetic defect ...
Psoriasis is a chronic relapsing, remitting interleukin (IL)-23/IL-17-driven skin disease mediated b...
SummaryInterleukin-23 (IL-23) and CD4+ T helper 17 (Th17) cells are thought to be critical in psoria...
Summary: Psoriasis is a chronic relapsing, remitting interleukin (IL)-23/IL-17-driven skin disease m...
Psoriasis is a common immune-mediated, chronic inflammatory skin disease characterized by widespread...
Regulatory T-cells (Treg) are crucial for immune homeostasis and prevention of immune pathology. Yet...
Regulatory T-cells (Treg) are crucial for immune homeostasis and prevention of immune pathology. Yet...
Abnormal production of inflammatory mediators is believed to play an important role in the pathogene...
Psoriasis is a chronic inflammatory disease mediated by a complex interplay between immune system an...
BACKGROUND: In the pathogenesis of psoriasis, proinflammatory T cells are strongly involved in the i...
Psoriasis is an autoimmune-related chronic inflammatory skin disease that is strongly associated wit...
Contains fulltext : 96935.pdf (publisher's version ) (Closed access)Psoriasis is a...
Psoriasis is one of the most common inflammatory skin conditions affecting both children and adults....
Psoriasis is a chronic inflammatory skin disease characterized by accelerated tumor necrosis factor-...
Psoriasis is a hereditary disease elicited by chronic activation of cutaneous T cells. Delineating t...
Regulatory T cells (Tregs) are crucial controllers of inflammation. Patients with a genetic defect ...
Psoriasis is a chronic relapsing, remitting interleukin (IL)-23/IL-17-driven skin disease mediated b...
SummaryInterleukin-23 (IL-23) and CD4+ T helper 17 (Th17) cells are thought to be critical in psoria...
Summary: Psoriasis is a chronic relapsing, remitting interleukin (IL)-23/IL-17-driven skin disease m...
Psoriasis is a common immune-mediated, chronic inflammatory skin disease characterized by widespread...
Regulatory T-cells (Treg) are crucial for immune homeostasis and prevention of immune pathology. Yet...
Regulatory T-cells (Treg) are crucial for immune homeostasis and prevention of immune pathology. Yet...
Abnormal production of inflammatory mediators is believed to play an important role in the pathogene...
Psoriasis is a chronic inflammatory disease mediated by a complex interplay between immune system an...
BACKGROUND: In the pathogenesis of psoriasis, proinflammatory T cells are strongly involved in the i...