Novel types of staphylococcal cassette chromosome mec elements identified in clonal complex 398 methicillin-resistant Staphylococcus aureus strains.
- Li, S.
- Skov, R.L.
- Han, X.
- Larsen, A.R.
- Larsen, J.
- Sorum, M.
- Wulf, M.
- Voss, A.
- Hiramatsu, K.
- Ito, T.
Publication date
January 2011
DOI Publisher
American Society for Microbiology ISSN
0066-4804Abstract
The structures of staphylococcal cassette chromosome mec (SCCmec) elements carried by 31 clonal complex 398 (CC398) methicillin-resistant Staphylococcus aureus (MRSA) strains isolated from the participants at a conference were analyzed. The SCCmecs were classified into novel types, namely, IX, X, V(5C2&5) subtype c, and IVa. Type V(5C2&5) subtype c, IX, and X SCCmecs carried genes conferring resistance to metals. The structures of SCCmecs from CC398 strains were distinct from those normally found in humans, adding to the evidence that humans are not the original host for CC398
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