Prostate and lymph node proton magnetic resonance (MR) spectroscopic imaging with external array coils at 3 T to detect recurrent prostate cancer after radiation therapy.
- Heijmink, S.W.T.P.J.
- Scheenen, T.W.J.
- Futterer, J.J.
- Klomp, D.W.J.
- Heesakkers, R.A.M.
- Hulsbergen-van de Kaa, C.A.
- Lin, E.N.J.T. van
- Heerschap, A.
- Barentsz, J.O.
DOIAbstract
In a patient suspected of having recurrent prostate cancer after radiation therapy, we demonstrate the feasibility of noninvasive proton magnetic resonance spectroscopic (1H-MRS) imaging of the prostate and a lymph node at 3 T using a matrix of external surface coils. Written informed consent was obtained from the patient. With 1H-MRS imaging, high choline with low citrate signal was observed in the prostate, and in the lymph node a signal of choline-containing compounds was identified. The tissue level of the compounds in the enlarged lymph node was estimated to be 8.1 mmol/kg water. Subsequent histopathological analysis of systematic transrectal ultrasound-guided prostate biopsy and computed tomography-guided biopsy of the lymph node conf...
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