BACKGROUND: The cause of chronic pancreatitis (CP) remains unknown. However, oxidative stress might play a role since recent animal studies have demonstrated that oxygen-free radicals contribute to the pathogenesis of experimental pancreatitis. Human serum paraoxonase (PON1) is an antioxidant enzyme that protects against cellular damage from oxidative stress. Genetic variations resulting in variable activity rates of this enzyme, are of toxicological and physiological importance. AIM: We investigated whether genetic polymorphisms of the PON1 gene modify the risk for CP. MATERIALS AND METHODS: DNA samples were obtained from 236 adult CP patients of hereditary (n = 23), alcoholic (n = 137), or idiopathic (n = 76) origin. DNA from 113 healthy ...
International audienceBackground: Excessive alcohol consumption has long been known to be the primar...
Vitamin D imbalance is suggested to be associated with the development of pancreatitis. Single nucle...
Chronic pancreatitis (CP) is a clinical situation with persisting inflammation leading to destructio...
Item does not contain fulltextBACKGROUND: The cause of chronic pancreatitis (CP) remains unknown. Ho...
Chronic pancreatitis (CP) is a progressive inflammatory disorder. A key characteristic of the condit...
AIMS: Alcohol misuse is now regarded as an important risk factor for development of chronic pancreat...
Aim of investigation. To estimate the role of genetic polymorphism (rs1800566) of NAD(F)H quinone ox...
INTRODUCTION:Chronic pancreatitis (CP) may be caused by oxidative stress. An important source of rea...
The purpose of this study was to investigate the possible role of PON-1, an antioxidant lipophilic e...
INTRODUCTION: Chronic pancreatitis (CP) may be caused by oxidative stress. An important source of re...
Chronic alcohol consumption is a major risk factor for the development of chronic pancreatitis. Howe...
Heme oxygenase 1 (HMOX1) is the rate limiting enzyme in heme degradation and a key regulator of infl...
<div><h3>Background</h3><p>Heme oxygenase 1 (HMOX1) is the rate limiting enzyme in heme degradation ...
Contains fulltext : 58394.pdf (publisher's version ) (Open Access)OBJECTIVES: Chro...
Background: Heme oxygenase 1 (HMOX1) is the rate limiting enzyme in heme degradation and a key regul...
International audienceBackground: Excessive alcohol consumption has long been known to be the primar...
Vitamin D imbalance is suggested to be associated with the development of pancreatitis. Single nucle...
Chronic pancreatitis (CP) is a clinical situation with persisting inflammation leading to destructio...
Item does not contain fulltextBACKGROUND: The cause of chronic pancreatitis (CP) remains unknown. Ho...
Chronic pancreatitis (CP) is a progressive inflammatory disorder. A key characteristic of the condit...
AIMS: Alcohol misuse is now regarded as an important risk factor for development of chronic pancreat...
Aim of investigation. To estimate the role of genetic polymorphism (rs1800566) of NAD(F)H quinone ox...
INTRODUCTION:Chronic pancreatitis (CP) may be caused by oxidative stress. An important source of rea...
The purpose of this study was to investigate the possible role of PON-1, an antioxidant lipophilic e...
INTRODUCTION: Chronic pancreatitis (CP) may be caused by oxidative stress. An important source of re...
Chronic alcohol consumption is a major risk factor for the development of chronic pancreatitis. Howe...
Heme oxygenase 1 (HMOX1) is the rate limiting enzyme in heme degradation and a key regulator of infl...
<div><h3>Background</h3><p>Heme oxygenase 1 (HMOX1) is the rate limiting enzyme in heme degradation ...
Contains fulltext : 58394.pdf (publisher's version ) (Open Access)OBJECTIVES: Chro...
Background: Heme oxygenase 1 (HMOX1) is the rate limiting enzyme in heme degradation and a key regul...
International audienceBackground: Excessive alcohol consumption has long been known to be the primar...
Vitamin D imbalance is suggested to be associated with the development of pancreatitis. Single nucle...
Chronic pancreatitis (CP) is a clinical situation with persisting inflammation leading to destructio...