Motivation: Genomics has revolutionized biological research, but quality assessment of the resulting assembled sequences is complicated and remains mostly limited to technical measures like N50. Results: We propose a measure for quantitative assessment of genome assembly and annotation completeness based on evolutionarily informed expectations of gene content. We implemented the assessment procedure in open-source software, with sets of Benchmarking Universal Single-Copy Orthologs, named BUSCO. Availability and implementation: Software implemented in Python and datasets available for download from http://busco.ezlab.org. Contact: evgeny.zdobnov@unige.ch Supplementary information: Supplementary data are available at Bioinformatics onlin
The availability of biological information in public databases has increased exponentially. To ensur...
Many inferences about the biological properties of an organism depend on the completeness and accura...
New sequencing technology has dramatically altered the landscape of whole-genome sequencing, allowin...
Genomics drives the current progress in molecular biology, generating unprecedented volumes of data....
Genomics promises comprehensive surveying of genomes and metagenomes, but rapidly changing technolog...
Genomics promises comprehensive surveying of genomes and metagenomes, but rapidly changing technolog...
Genome sequencing is becoming cheaper and faster thanks to the introduction of next-generation seque...
The increasing affordability of sequencing technologies offers many new and exciting opportunities t...
Ambitious initiatives to coordinate genome sequencing of Earth's biodiversity mean that the accumula...
The current revolution in genomics has been made possible by software tools called genome assemblers...
Background: The process of generating raw genome sequence data continues to become cheaper, faster, ...
Background: The process of generating raw genome sequence data continues to become cheaper, faster,...
Background: The process of generating raw genome sequence data continues to become cheaper, faster, ...
In the fourteen years since the announcement of the rough draft of the human genome there has been a...
Genome assembly is a critical first step for biological discovery. All current sequencing technologi...
The availability of biological information in public databases has increased exponentially. To ensur...
Many inferences about the biological properties of an organism depend on the completeness and accura...
New sequencing technology has dramatically altered the landscape of whole-genome sequencing, allowin...
Genomics drives the current progress in molecular biology, generating unprecedented volumes of data....
Genomics promises comprehensive surveying of genomes and metagenomes, but rapidly changing technolog...
Genomics promises comprehensive surveying of genomes and metagenomes, but rapidly changing technolog...
Genome sequencing is becoming cheaper and faster thanks to the introduction of next-generation seque...
The increasing affordability of sequencing technologies offers many new and exciting opportunities t...
Ambitious initiatives to coordinate genome sequencing of Earth's biodiversity mean that the accumula...
The current revolution in genomics has been made possible by software tools called genome assemblers...
Background: The process of generating raw genome sequence data continues to become cheaper, faster, ...
Background: The process of generating raw genome sequence data continues to become cheaper, faster,...
Background: The process of generating raw genome sequence data continues to become cheaper, faster, ...
In the fourteen years since the announcement of the rough draft of the human genome there has been a...
Genome assembly is a critical first step for biological discovery. All current sequencing technologi...
The availability of biological information in public databases has increased exponentially. To ensur...
Many inferences about the biological properties of an organism depend on the completeness and accura...
New sequencing technology has dramatically altered the landscape of whole-genome sequencing, allowin...