The failure of remyelination in multiple sclerosis is largely unexplained. Lindner et al. report that glial cells in demyelinating lesions show increased expression of fibroblast growth factor 9 (FGF9). This induces astrocyte-dependent responses that inhibit remyelination and stimulate expression of pro-inflammatory chemokines, supporting a feedback loop that amplifies disease activit
Fibroblast growth factors (FGFs) and their receptors (FGFRs) are involved in demyelinating pathologi...
A pathological hallmark of multiple sclerosis (MS) is myelin loss in brain white matter accompanied ...
Central nervous system remyelination by oligodendrocyte progenitor cells (OPCs) ultimately fails in ...
Remyelination failure plays an important role in the pathophysiology of multiple sclerosis, but the ...
Multiple sclerosis (MS) is a chronic demyelinating disease of the central nervous system. In around ...
Fibroblast growth factor (FGF) signaling contributes to failure of remyelination in multiple scleros...
Chronic demyelination is a pathological hallmark of multiple sclerosis (MS). Only a minority of MS l...
Chronic demyelination is a pathological hallmark of multiple sclerosis (MS). Only a minority of MS l...
Multiple sclerosis (MS) is a chronic inflammatory and neurodegenerative disease of the central nervo...
Aims: Fibroblast growth factor (FGF) signalling is dysregulated in multiple sclerosis (MS) and othe...
Analysis of the effects of three members of the FGF family (FGF1, FGF2 and FGF9) and bone morphogeni...
Fibroblast growth factor (FGF) signaling is involved in the pathogenesis of multiple sclerosis (MS)....
Our central nervous system functions, among others, thanks to myelin. Myelin is a fatty layer of ins...
AbstractMyelin, a dielectric sheath that wraps large axons in the central and peripheral nervous sys...
In der vorliegenden Arbeit wurde der Einfluss des Fibroblast Growth Factor 9 (FGF-9) auf die Remyeli...
Fibroblast growth factors (FGFs) and their receptors (FGFRs) are involved in demyelinating pathologi...
A pathological hallmark of multiple sclerosis (MS) is myelin loss in brain white matter accompanied ...
Central nervous system remyelination by oligodendrocyte progenitor cells (OPCs) ultimately fails in ...
Remyelination failure plays an important role in the pathophysiology of multiple sclerosis, but the ...
Multiple sclerosis (MS) is a chronic demyelinating disease of the central nervous system. In around ...
Fibroblast growth factor (FGF) signaling contributes to failure of remyelination in multiple scleros...
Chronic demyelination is a pathological hallmark of multiple sclerosis (MS). Only a minority of MS l...
Chronic demyelination is a pathological hallmark of multiple sclerosis (MS). Only a minority of MS l...
Multiple sclerosis (MS) is a chronic inflammatory and neurodegenerative disease of the central nervo...
Aims: Fibroblast growth factor (FGF) signalling is dysregulated in multiple sclerosis (MS) and othe...
Analysis of the effects of three members of the FGF family (FGF1, FGF2 and FGF9) and bone morphogeni...
Fibroblast growth factor (FGF) signaling is involved in the pathogenesis of multiple sclerosis (MS)....
Our central nervous system functions, among others, thanks to myelin. Myelin is a fatty layer of ins...
AbstractMyelin, a dielectric sheath that wraps large axons in the central and peripheral nervous sys...
In der vorliegenden Arbeit wurde der Einfluss des Fibroblast Growth Factor 9 (FGF-9) auf die Remyeli...
Fibroblast growth factors (FGFs) and their receptors (FGFRs) are involved in demyelinating pathologi...
A pathological hallmark of multiple sclerosis (MS) is myelin loss in brain white matter accompanied ...
Central nervous system remyelination by oligodendrocyte progenitor cells (OPCs) ultimately fails in ...