BACKGROUND: Direct myocardial effects of volatile anesthetics have been studied in various animal species in vitro. This study evaluated the effects of equianesthetic concentrations of desflurane, sevoflurane, isoflurane, and halothane on contractile parameters of isolated human atria in vitro. METHODS: Human right atrial trabeculae, obtained from patients undergoing coronary bypass surgery, were studied in an oxygenated (95% O2-5% CO2) Tyrode's modified solution ([Ca2+]o = 2.0 mM, 30 degrees C, stimulation frequency 0.5 Hz). The effects of equianesthetic concentrations (0.5, 1, 1.5, 2, and 2.5 minimum alveolar concentration [MAC]) of desflurane, sevoflurane, isoflurane, and halothane on inotropic and lusitropic parameters of isometric tw...
The authors sought to determine if isoflurane would attenuate effects of three different types of va...
AIM: We tested the hypothesis that brief exposure to desflurane at the time of reoxygenation migh...
Objective The actions of volatile anesthetics on left ventricular (LV) function in normal and failin...
BACKGROUND: We examined the role of reactive oxygen species (ROS) in sevoflurane- and desflurane-in...
BACKGROUND: The effects of anesthetic concentrations of sevoflurane were studied in isolated myocard...
BACKGROUND: The authors examined the role of adenosine triphosphate-sensitive potassium channels an...
BACKGROUND: The authors determined whether desflurane altered myocardial excitation-contraction coup...
The volatile anesthetics are a class of general anesthetic drugs used by the perfusionist during car...
Dose-related depression of left ventricular function or cardiac output has been reported in humans a...
BACKGROUND: The authors examined the role of adenosine triphosphate-sensitive potassium (K(ATP)) ch...
This study was designed to examine the effects of inhalation anaesthetics on function and metabolism...
BACKGROUND: The role of phosphatidylinositol-3-kinase (PI3K) in sevoflurane- and desflurane-induced...
BACKGROUND: Isoflurane and sevoflurane have been shown to elicit myocardial postconditioning, but t...
Myocardial conditioning is actually an essential strategy in the management of ischaemia-reperfusion...
of halothane, isoflurane, and sevoflurane on elastic stiffness, which reflects the degree of cross-b...
The authors sought to determine if isoflurane would attenuate effects of three different types of va...
AIM: We tested the hypothesis that brief exposure to desflurane at the time of reoxygenation migh...
Objective The actions of volatile anesthetics on left ventricular (LV) function in normal and failin...
BACKGROUND: We examined the role of reactive oxygen species (ROS) in sevoflurane- and desflurane-in...
BACKGROUND: The effects of anesthetic concentrations of sevoflurane were studied in isolated myocard...
BACKGROUND: The authors examined the role of adenosine triphosphate-sensitive potassium channels an...
BACKGROUND: The authors determined whether desflurane altered myocardial excitation-contraction coup...
The volatile anesthetics are a class of general anesthetic drugs used by the perfusionist during car...
Dose-related depression of left ventricular function or cardiac output has been reported in humans a...
BACKGROUND: The authors examined the role of adenosine triphosphate-sensitive potassium (K(ATP)) ch...
This study was designed to examine the effects of inhalation anaesthetics on function and metabolism...
BACKGROUND: The role of phosphatidylinositol-3-kinase (PI3K) in sevoflurane- and desflurane-induced...
BACKGROUND: Isoflurane and sevoflurane have been shown to elicit myocardial postconditioning, but t...
Myocardial conditioning is actually an essential strategy in the management of ischaemia-reperfusion...
of halothane, isoflurane, and sevoflurane on elastic stiffness, which reflects the degree of cross-b...
The authors sought to determine if isoflurane would attenuate effects of three different types of va...
AIM: We tested the hypothesis that brief exposure to desflurane at the time of reoxygenation migh...
Objective The actions of volatile anesthetics on left ventricular (LV) function in normal and failin...