Optical coherence tomography in respiratory science and medicine: from airways to alveoli

Optical coherence tomography is a rapidly maturing optical imaging technology, enabling study of the in vivo structure of lung tissue at a scale of tens of micrometers. It has been used to assess the layered structure of airway walls, quantify both airway lumen caliber and compliance, and image individual alveoli. This article provides an overview of the technology and reviews its capability to provide new insights into respiratory disease.Robert A. McLaughlin, Peter B. Noble, and David D. Sampso