Este trabalho foi financiado pelo Concurso Anual para Projetos de Investigação, Desenvolvimento, Inovação e Criação Artística (IDI&CA) 2016 do Instituto Politécnico de Lisboa. Código de referência: IPL/2016/TBCCentro_ESTeSLCilia are hair-like appendages, consisting of a microtubule (MT)-based ciliary axoneme, that fulfill critical motility and sensory functions required for normal embryonic development and also for homeostasis of adult tissues. At their base, cilia have a centriole/basal body, which can be derived from the centrosome, and that nucleates the ciliary axoneme (primary cilia). Centrosomes consist of a pair of centrioles surrounded by the pericentriolar matrix that nucleate/organize the cytoskeleton and are implicated in cell mi...
The OFD1 gene was initially identified as the gene responsible for the X-linked dominant male lethal...
In animal cells the centrosome is positioned at the cell centre in close association with the nucleu...
The primary cilium is a microtubule-based sensory organelle that dynamically links signalling pathwa...
Este trabalho foi financiado pelo Concurso Anual para Projetos de Investigação, Desenvolvimento, Ino...
Cilia are microtubule-based organelles that protrude from the cell surface and fulfill critical moti...
Project IPL/2019/MOONOFCILI/ESTeSLAims/Context: Primary cilia are specialized microtubule-based sign...
Tese de mestrado, Bioquímica (Bioquímica Médica) Universidade de Lisboa, Faculdade de Ciências, 2019...
Successful cilia assembly requires correct positioning and anchoring of the centrosome's mother cent...
Centrosomes are the major microtubule organizing centers in animal cells. Each centrosome comprises ...
The balance of protein synthesis and degradation is finely regulated and influences cellular homeost...
Primary cilia were once considered vestigial structures with no obvious function. However, it is now...
The deposited article is a post-print version (NIH-PA Author Manuscript) and has been submitted to p...
Primary cilia were once considered vestigial structures with no obvious function. However, it is now...
Primary cilia are non-motile organelles associated with the cell cycle, which can be found in most v...
Oral-facial-digital type I syndrome (OFDI; OMIM 311200) is an X-linked dominant developmental ciliop...
The OFD1 gene was initially identified as the gene responsible for the X-linked dominant male lethal...
In animal cells the centrosome is positioned at the cell centre in close association with the nucleu...
The primary cilium is a microtubule-based sensory organelle that dynamically links signalling pathwa...
Este trabalho foi financiado pelo Concurso Anual para Projetos de Investigação, Desenvolvimento, Ino...
Cilia are microtubule-based organelles that protrude from the cell surface and fulfill critical moti...
Project IPL/2019/MOONOFCILI/ESTeSLAims/Context: Primary cilia are specialized microtubule-based sign...
Tese de mestrado, Bioquímica (Bioquímica Médica) Universidade de Lisboa, Faculdade de Ciências, 2019...
Successful cilia assembly requires correct positioning and anchoring of the centrosome's mother cent...
Centrosomes are the major microtubule organizing centers in animal cells. Each centrosome comprises ...
The balance of protein synthesis and degradation is finely regulated and influences cellular homeost...
Primary cilia were once considered vestigial structures with no obvious function. However, it is now...
The deposited article is a post-print version (NIH-PA Author Manuscript) and has been submitted to p...
Primary cilia were once considered vestigial structures with no obvious function. However, it is now...
Primary cilia are non-motile organelles associated with the cell cycle, which can be found in most v...
Oral-facial-digital type I syndrome (OFDI; OMIM 311200) is an X-linked dominant developmental ciliop...
The OFD1 gene was initially identified as the gene responsible for the X-linked dominant male lethal...
In animal cells the centrosome is positioned at the cell centre in close association with the nucleu...
The primary cilium is a microtubule-based sensory organelle that dynamically links signalling pathwa...