Cartilage lesions can progress into secondary osteoarthritis and cause severe clinical problems in numerous patients. As a prospective treatment of such lesions, human-derived induced pluripotent stem cells (iPSCs) were shown to be 3D bioprinted into cartilage mimics using a nanofibrillated cellulose (NFC) composite bioink when co-printed with irradiated human chondrocytes. Two bioinks were investigated: NFC with alginate (NFC/A) or hyaluronic acid (NFC/HA). Low proliferation and phenotypic changes away from pluripotency were seen in the case of NFC/HA. However, in the case of the 3D-bioprinted NFC/A (60/40, dry weight % ratio) constructs, pluripotency was initially maintained, and after five weeks, hyaline-like cartilaginous tissue with co...
Cartilage lesions fail to heal spontaneously, leading to the development of chronic conditions which...
Bioprinting is a promising tool to fabricate well-organized cell-laden constructs for repair and reg...
Three-dimensional (3D) bioprinting is driving major innovations in the area of cartilage tissue engi...
Cartilage lesions can progress into secondary osteoarthritis and cause severe clinical problems in n...
\ua9 2016 Elsevier B.V.Auricular cartilage tissue engineering (TE) aims to provide an effective trea...
Cartilage repair and replacement is a major challenge in plastic reconstructive surgery. The develop...
<div><p>Cartilage repair and replacement is a major challenge in plastic reconstructive surgery. The...
3D bioprinting offers interesting opportunities for 3D tissue printing by providing living cells wit...
Background: The three-dimensional (3D) bioprinting technology allows creation of 3D constructs in a ...
Cartilage defects can impair the most elementary daily activities and, if not properly treated, can ...
The introduction of 3D bioprinting is expected to revolutionize the field of tissue engineering and ...
Cartilage is a connective tissue which a limited capacity for healing and repairing. In this context...
Cell-laden hydrogels are the primary building blocks for bioprinting, and, also termed bioinks, are ...
To date, the treatment of articular cartilage lesions remains challenging. A promising strategy for ...
Cell-laden hydrogels are the primary building blocks for bioprinting, and, also termed bioinks, are ...
Cartilage lesions fail to heal spontaneously, leading to the development of chronic conditions which...
Bioprinting is a promising tool to fabricate well-organized cell-laden constructs for repair and reg...
Three-dimensional (3D) bioprinting is driving major innovations in the area of cartilage tissue engi...
Cartilage lesions can progress into secondary osteoarthritis and cause severe clinical problems in n...
\ua9 2016 Elsevier B.V.Auricular cartilage tissue engineering (TE) aims to provide an effective trea...
Cartilage repair and replacement is a major challenge in plastic reconstructive surgery. The develop...
<div><p>Cartilage repair and replacement is a major challenge in plastic reconstructive surgery. The...
3D bioprinting offers interesting opportunities for 3D tissue printing by providing living cells wit...
Background: The three-dimensional (3D) bioprinting technology allows creation of 3D constructs in a ...
Cartilage defects can impair the most elementary daily activities and, if not properly treated, can ...
The introduction of 3D bioprinting is expected to revolutionize the field of tissue engineering and ...
Cartilage is a connective tissue which a limited capacity for healing and repairing. In this context...
Cell-laden hydrogels are the primary building blocks for bioprinting, and, also termed bioinks, are ...
To date, the treatment of articular cartilage lesions remains challenging. A promising strategy for ...
Cell-laden hydrogels are the primary building blocks for bioprinting, and, also termed bioinks, are ...
Cartilage lesions fail to heal spontaneously, leading to the development of chronic conditions which...
Bioprinting is a promising tool to fabricate well-organized cell-laden constructs for repair and reg...
Three-dimensional (3D) bioprinting is driving major innovations in the area of cartilage tissue engi...