Primary immunodeficiencies (PIDs) constitute a large group of rare disorders that affect the function of the immune system. A specific group of PIDs entitled “diseases of immune dysregulation” are developed due to mutation in the genes which have critical roles in the regulation of immune responses and immunological tolerance. This group of PID patients develop autoimmune and inflammatory disorders as a result of their impaired immunity, therefore they could be considered as a model for analyzing the link between immune dysregulation and autoimmunity. In this article, our aim is to describe the function of the mutated gene, the molecular and cellular mechanisms underlying the immune dysregulation and review the literature in regard with the...
The pathology of immune system can lead to immune disorders. Immunodeficencies are caused by insuffi...
In recent years, the field of primary immunodeficienciency diseases (PID) has experienced remarkable...
The immune system is crucial for defense against external pathogens and a fine tuned balance of its ...
The primary immunodeficiency diseases (PIDs) include many genetic disorders that affect different co...
Background Primary Immunodeficiencies (PIDs) represent unique opportunities to understand the operat...
Primary immunodeficiencies (PID) comprise a diverse group of clinical disorders with varied genetic ...
To access publisher full text version of this article. Please click on the hyperlink in Additional L...
Background Immune dysregulation is as important as susceptibility to infection in defining primar...
During the last years, studies investigating the intriguing association between immunodeficiency and...
2 Background: Primary immunodeficiency diseases (PIDs) comprise a genetically heterogeneous group of...
© 2019 Charlotte Ann SladePrimary Immunodeficiencies (PIDs) are a heterogeneous collection of severa...
Primary immunodeficiencies (PIDs) are a heterogeneous group of disorders causing immune dysfunction ...
Primary immunodeficiencies (PIDs) are inherited disorders classically characterized by increased sus...
Background Several primary immune deficiency disorders are associated with autoimmunity and malignan...
Partial T-cell immunodeficiencies constitute a heterogeneous cluster of disorders characterized by a...
The pathology of immune system can lead to immune disorders. Immunodeficencies are caused by insuffi...
In recent years, the field of primary immunodeficienciency diseases (PID) has experienced remarkable...
The immune system is crucial for defense against external pathogens and a fine tuned balance of its ...
The primary immunodeficiency diseases (PIDs) include many genetic disorders that affect different co...
Background Primary Immunodeficiencies (PIDs) represent unique opportunities to understand the operat...
Primary immunodeficiencies (PID) comprise a diverse group of clinical disorders with varied genetic ...
To access publisher full text version of this article. Please click on the hyperlink in Additional L...
Background Immune dysregulation is as important as susceptibility to infection in defining primar...
During the last years, studies investigating the intriguing association between immunodeficiency and...
2 Background: Primary immunodeficiency diseases (PIDs) comprise a genetically heterogeneous group of...
© 2019 Charlotte Ann SladePrimary Immunodeficiencies (PIDs) are a heterogeneous collection of severa...
Primary immunodeficiencies (PIDs) are a heterogeneous group of disorders causing immune dysfunction ...
Primary immunodeficiencies (PIDs) are inherited disorders classically characterized by increased sus...
Background Several primary immune deficiency disorders are associated with autoimmunity and malignan...
Partial T-cell immunodeficiencies constitute a heterogeneous cluster of disorders characterized by a...
The pathology of immune system can lead to immune disorders. Immunodeficencies are caused by insuffi...
In recent years, the field of primary immunodeficienciency diseases (PID) has experienced remarkable...
The immune system is crucial for defense against external pathogens and a fine tuned balance of its ...