Add to ORKGChemical investigations of the chemistry of Fijian reef systems have yielded the discovery of an iodinated diterpene-benzoate produced by the Fijian red macroalga Callophycus sp. Through the use of bioassay guided fractionation, NMR and mass spectrometric-based structural elucidation, diiodocallophycoic acid (1) was successfully isolated and structurally characterized. This novel secondary metabolite was found to contain two highly unusual exocyclic iodinated olefins and demonstrated moderate biological activity against methicillin resistant Staphylococcus aureus (MRSA) with an MIC of 3.9 μg/mL.Undergraduat
Natural products have been used since ancient times to treat illnesses and terrestrial organisms hav...
Soft corals (phylum Cnidaria) are known to produce diverse marine secondary metabolites which play ...
A detailed examination of the red alga Callophycus serratus collected in Tonga led to the isolation ...
Unique iodine-containing meroditerpenes iodocallophycoic acid A (1) and iodocallophycols A–D (2–5) w...
Bioassay-guided fractionation of extracts from a Fijian red alga in the genus Callophycus resulted i...
Unique iodine-containing meroditerpenes iodocallophycoic acid A (<b>1</b>) and iodocallophycols A–D ...
Bioassay-guided fractionation of extracts from a Fijian red alga in the genus <i>Callophycus</i> res...
An NMR- and MS-directed study led to the isolation and structure elucidation of several halogenated ...
Red macroalgae are well-known for the production of brominated metabolites, including terpenoids and...
Bromophycolides C-I (1-7) were isolated from extracts of the Fijian red alga Callophycus serratus...
Marine organisms are known to produce secondary metabolites which have novel structures and are ofte...
Marine organisms are widely recognized sources of an impressive array of structurally unusual compou...
Ph.D. University of Hawaii at Manoa 2010.Includes bibliographical references.Studies directed toward...
One solution to the global crisis of antibiotic resistance is the discovery of novel antimicrobial c...
This thesis presents results obtained from the investigation of secondary metabolites through screen...
Natural products have been used since ancient times to treat illnesses and terrestrial organisms hav...
Soft corals (phylum Cnidaria) are known to produce diverse marine secondary metabolites which play ...
A detailed examination of the red alga Callophycus serratus collected in Tonga led to the isolation ...
Unique iodine-containing meroditerpenes iodocallophycoic acid A (1) and iodocallophycols A–D (2–5) w...
Bioassay-guided fractionation of extracts from a Fijian red alga in the genus Callophycus resulted i...
Unique iodine-containing meroditerpenes iodocallophycoic acid A (<b>1</b>) and iodocallophycols A–D ...
Bioassay-guided fractionation of extracts from a Fijian red alga in the genus <i>Callophycus</i> res...
An NMR- and MS-directed study led to the isolation and structure elucidation of several halogenated ...
Red macroalgae are well-known for the production of brominated metabolites, including terpenoids and...
Bromophycolides C-I (1-7) were isolated from extracts of the Fijian red alga Callophycus serratus...
Marine organisms are known to produce secondary metabolites which have novel structures and are ofte...
Marine organisms are widely recognized sources of an impressive array of structurally unusual compou...
Ph.D. University of Hawaii at Manoa 2010.Includes bibliographical references.Studies directed toward...
One solution to the global crisis of antibiotic resistance is the discovery of novel antimicrobial c...
This thesis presents results obtained from the investigation of secondary metabolites through screen...
Natural products have been used since ancient times to treat illnesses and terrestrial organisms hav...
Soft corals (phylum Cnidaria) are known to produce diverse marine secondary metabolites which play ...
A detailed examination of the red alga Callophycus serratus collected in Tonga led to the isolation ...