Add to ORKGNew electron transfer moiety labeled nucleic acid analogue probes are provided that can be used in methods for determining nucleic acids in a sample. The new probes can be prepared using novel monomer subunits in a chemical synthesis route. The nucleic acids can be determined by binding the probe molecules to the nucleic acid and inducing electron transfer within the complex formed. The occurrence of the electron transfer is determined as a measure of the nucleic acid.Georgia Tech Research Corp.Roche Diagnostics Gmb
The synthesis of two analogues of Aromatic Peptide Nucleic Acids (APNAs) monomers was successfully a...
Peptide nucleic acids (PNAs) are oligonucleotide mimics widely used as antisense, antigene molecules...
<p>This dissertation is focused on the study of properties of PNA relevant for its use as a new mate...
New electron transfer moiety labeled nucleic acid analogue probes are provided that can be used in m...
Fluorogenic oligonucleotide probes that can produce a change in fluorescence signal upon binding to ...
PNA is a synthetic analog of DNA in which the sugar diphosphate backbone is replaced by a polyamide ...
121-129A novel PNA monomer with adenine nucleobase and a modified backbone with charged and a met...
Halogen-labelled peptide organic acid (HPOA) monomers have been synthesised and incorporated into se...
Peptide Nucleic Acids (PNAs), nucleic acid analogues showing high stability to enzyme degradation an...
Peptide nucleic acids (PNAs) are oligonucleotide mimics widely used as antisense, antigene molecule...
PNA oligomers are promising candidates as DNA probes on account of their very high DNA binding power...
This study provides insight into the mechanism of capturing low energy electrons by peptide nucleic ...
Progress in genome research led to new perspectives in diagnostic applications and to new promising ...
Single-stranded nucleic acid molecules can interact under certain conditions with other nucleic acid...
Synthesis of new monomers and oligomers of modified peptide nucleic acids with diagnostic and potent...
The synthesis of two analogues of Aromatic Peptide Nucleic Acids (APNAs) monomers was successfully a...
Peptide nucleic acids (PNAs) are oligonucleotide mimics widely used as antisense, antigene molecules...
<p>This dissertation is focused on the study of properties of PNA relevant for its use as a new mate...
New electron transfer moiety labeled nucleic acid analogue probes are provided that can be used in m...
Fluorogenic oligonucleotide probes that can produce a change in fluorescence signal upon binding to ...
PNA is a synthetic analog of DNA in which the sugar diphosphate backbone is replaced by a polyamide ...
121-129A novel PNA monomer with adenine nucleobase and a modified backbone with charged and a met...
Halogen-labelled peptide organic acid (HPOA) monomers have been synthesised and incorporated into se...
Peptide Nucleic Acids (PNAs), nucleic acid analogues showing high stability to enzyme degradation an...
Peptide nucleic acids (PNAs) are oligonucleotide mimics widely used as antisense, antigene molecule...
PNA oligomers are promising candidates as DNA probes on account of their very high DNA binding power...
This study provides insight into the mechanism of capturing low energy electrons by peptide nucleic ...
Progress in genome research led to new perspectives in diagnostic applications and to new promising ...
Single-stranded nucleic acid molecules can interact under certain conditions with other nucleic acid...
Synthesis of new monomers and oligomers of modified peptide nucleic acids with diagnostic and potent...
The synthesis of two analogues of Aromatic Peptide Nucleic Acids (APNAs) monomers was successfully a...
Peptide nucleic acids (PNAs) are oligonucleotide mimics widely used as antisense, antigene molecules...
<p>This dissertation is focused on the study of properties of PNA relevant for its use as a new mate...