Add to ORKGThe chick embryonic midbrain offers an effective model to monitor the effects of gene overexpression or knockdown on neural progenitor differentiation at multiple different points during development. To better characterize the effect of gene manipulation by in ovoelectroporation, we are using quantitative PCR to screen the effect of gene overexpression on markers of neural progenitor differentiation, followed by anatomical analysis of interesting candidate genes. These approaches are undertaken with undergraduate researchers, providing an optimal forum to reinforce principles of developmental biology and also to identify and characterize unknown genes or genetic mutants. These approaches can be applied broadly to allow investigators to read...
The chicken embryo has been used as a classical embryological model for studying developmental event...
The chicken spinal cord is an excellent model for the study of early neural development in vertebrat...
The molecular changes underlying neural progenitor differentiation are essentially unknown. We appli...
The chick embryonic midbrain offers an effective model to monitor the effects of gene overexpression...
Despite the development of brain organoids and neural cultures derived from iPSCs (induced pluripote...
International audienceBackground: During the development of the central nervous system (CNS), patter...
An obstacle in stem cell biology is revealing signaling pathways that drive stem cells to mature int...
Many genes have several, sometimes divergent functions during development. Therefore, timing of gene...
Abstract The embryonic chick occupies a privileged place among animal models used in developmental s...
Understanding events that regulate the generation of multiple cell and tissue types during mammalian...
Markers expressed in the developing embryo can distinguish different areas of the nervous system. Sp...
Stem cells have significant potential for tissue engineer-ing and regeneration, and neural stem and ...
Signalling pathways that regulate neural progenitor proliferation and neuronal differentiation have ...
As neuronal differentiation of embryonic stem cells (ESCs) recapitulates embryonic neurogenesis, dis...
Genomics has changed the pace by which genes are analyzed. Rather than looking at genes one by one, ...
The chicken embryo has been used as a classical embryological model for studying developmental event...
The chicken spinal cord is an excellent model for the study of early neural development in vertebrat...
The molecular changes underlying neural progenitor differentiation are essentially unknown. We appli...
The chick embryonic midbrain offers an effective model to monitor the effects of gene overexpression...
Despite the development of brain organoids and neural cultures derived from iPSCs (induced pluripote...
International audienceBackground: During the development of the central nervous system (CNS), patter...
An obstacle in stem cell biology is revealing signaling pathways that drive stem cells to mature int...
Many genes have several, sometimes divergent functions during development. Therefore, timing of gene...
Abstract The embryonic chick occupies a privileged place among animal models used in developmental s...
Understanding events that regulate the generation of multiple cell and tissue types during mammalian...
Markers expressed in the developing embryo can distinguish different areas of the nervous system. Sp...
Stem cells have significant potential for tissue engineer-ing and regeneration, and neural stem and ...
Signalling pathways that regulate neural progenitor proliferation and neuronal differentiation have ...
As neuronal differentiation of embryonic stem cells (ESCs) recapitulates embryonic neurogenesis, dis...
Genomics has changed the pace by which genes are analyzed. Rather than looking at genes one by one, ...
The chicken embryo has been used as a classical embryological model for studying developmental event...
The chicken spinal cord is an excellent model for the study of early neural development in vertebrat...
The molecular changes underlying neural progenitor differentiation are essentially unknown. We appli...