IF 2.824International audienceThe clinical use of bleomycin is restrained because of its lung toxicity with pulmonary fibrosis being the most devastating form. Toxic and idiopathic pulmonary fibrosis (PF) start classically in the subpleural area. It is known that 1) pleural mesothelial cells (PMCs) acquire a TGF-beta1-induced myofibroblast phenotype and 2) inflammation plays a significant role in fibrogenesis. The role of mesothelial cells in PF and in bleomycin lung toxicity has still to be investigated.C57Bl/6 mice were intravenously injected with bleomycin or NaCl. Repeated intravenous bleomycin induces a peculiar lung fibrotic response with 1) an histological peripheral distribution, 2) a collagen accumulation in pleural and subpleural ...
<p>The numbers of BALF inflammatory cells increased after either a single (<b>A</b>) or repetitive (...
Idiopathic pulmonary fibrosis (IPF) is a distressing lung disorder with poor prognosis and high mort...
2004.—Administration of bleomycin (BM) produces inflammation and fibrosis of the lung in humans and ...
IF 2.824International audienceThe clinical use of bleomycin is restrained because of its lung toxici...
IF 10.569International audienceIntroduction: In patients, the therapeutic use of bleomycin (BLM), a ...
Background: Idiopathic and toxic pulmonary fibrosis are severe diseases starting classically in the ...
AbstractIdiopathic pulmonary fibrosis (IPF) is a chronic progressive lung disease characterized by t...
Bleomycin (BLM) is a drug used to treat different types of neoplasms. BLM’s most severe adverse effe...
La fibrose pulmonaire (FP) idiopathique est une maladie sans traitement efficace caractérisée par un...
Abstract Background Pulmonary fibrosis is a progressive and lethal disease characterized by damage t...
It is well-known that bleomycin-induced pulmonary fibrosis is difficult to produce in BALB/c mice. T...
<div><p>A–F: MMP-13<sup>-</sup>/<sup>-</sup> and WT mice were exposed to saline (control) or bleomyc...
<div><p>The preclinical model of bleomycin-induced lung fibrosis, used to investigate mechanisms rel...
Background: Pulmonary hypertension (PH) is a common complication of idiopathic pulmonary fibrosis (I...
The preclinical model of bleomycin-induced lung fibrosis, used to investigate mechanisms related to ...
<p>The numbers of BALF inflammatory cells increased after either a single (<b>A</b>) or repetitive (...
Idiopathic pulmonary fibrosis (IPF) is a distressing lung disorder with poor prognosis and high mort...
2004.—Administration of bleomycin (BM) produces inflammation and fibrosis of the lung in humans and ...
IF 2.824International audienceThe clinical use of bleomycin is restrained because of its lung toxici...
IF 10.569International audienceIntroduction: In patients, the therapeutic use of bleomycin (BLM), a ...
Background: Idiopathic and toxic pulmonary fibrosis are severe diseases starting classically in the ...
AbstractIdiopathic pulmonary fibrosis (IPF) is a chronic progressive lung disease characterized by t...
Bleomycin (BLM) is a drug used to treat different types of neoplasms. BLM’s most severe adverse effe...
La fibrose pulmonaire (FP) idiopathique est une maladie sans traitement efficace caractérisée par un...
Abstract Background Pulmonary fibrosis is a progressive and lethal disease characterized by damage t...
It is well-known that bleomycin-induced pulmonary fibrosis is difficult to produce in BALB/c mice. T...
<div><p>A–F: MMP-13<sup>-</sup>/<sup>-</sup> and WT mice were exposed to saline (control) or bleomyc...
<div><p>The preclinical model of bleomycin-induced lung fibrosis, used to investigate mechanisms rel...
Background: Pulmonary hypertension (PH) is a common complication of idiopathic pulmonary fibrosis (I...
The preclinical model of bleomycin-induced lung fibrosis, used to investigate mechanisms related to ...
<p>The numbers of BALF inflammatory cells increased after either a single (<b>A</b>) or repetitive (...
Idiopathic pulmonary fibrosis (IPF) is a distressing lung disorder with poor prognosis and high mort...
2004.—Administration of bleomycin (BM) produces inflammation and fibrosis of the lung in humans and ...