Kisspeptin-Gpr54 signaling is critical for the GnRH neuronal network controlling fertility. The present study reports on a kisspeptin (Kiss)-green fluorescent protein (GFP) mouse model enabling brain slice electrophysiological recordings to be made from Kiss neurons in the arcuate nucleus (ARN) and rostral periventricular region of the third ventricle (RP3V). Using dual immunofluorescence, approximately 90% of GFP cells in the RP3V of females, and ARN in both sexes, are shown to be authentic Kiss-synthesizing neurons in adult mice. Cell-attached recordings of ARN Kiss-GFP cells revealed a marked sex difference in their mean firing rates; 90% of Kiss-GFP cells in males exhibited slow irregular firing (0.17 ± 0.04 Hz) whereas neurons from die...
The neuropeptide kisspeptin, encoded by Kiss1, regulates reproduction by stimulating GnRH secretion....
The neuropeptide kisspeptin, encoded by Kiss1, regulates reproduction by stimulating GnRH secretion....
It is now well established that the kisspeptin neurons of the hypothalamus play a key role in regula...
Kisspeptin-Gpr54 signaling is critical for the GnRH neuronal network controlling fertility. The pres...
The gonadotropin-releasing hormone (GnRH) neurons are the principal neurons in a network within the ...
The gonadotropin-releasing hormone (GnRH) neurons are the principal neurons in a network within the ...
Kisspeptin neurons are critical components of the neuronal network controlling the activity of the g...
The neuropeptide kisspeptin is a potent stimulator of GnRH neurons and has been implicated as a majo...
Kisspeptin, encoded by Kiss1, stimulates GnRH neurons to govern reproduction. In rodents, estro-gen-...
Kisspeptin, encoded by Kiss1, stimulates GnRH neurons to govern reproduction. In rodents, estrogen-s...
Kisspeptin, encoded by Kiss1, stimulates GnRH neurons to govern reproduction. In rodents, estrogen-s...
Reproduction and fertility in mammals is critically dependent on the neurosecretion of gonadotrophin...
Reproduction and fertility in mammals is critically dependent on the neurosecretion of gonadotrophin...
Kisspeptin (encoded by Kiss1), a neuropeptide critically involved in neuroendocrine regulation of re...
Kisspeptin is a potent activator of GnRH-induced gonadotropin secretion and is a proposed central re...
The neuropeptide kisspeptin, encoded by Kiss1, regulates reproduction by stimulating GnRH secretion....
The neuropeptide kisspeptin, encoded by Kiss1, regulates reproduction by stimulating GnRH secretion....
It is now well established that the kisspeptin neurons of the hypothalamus play a key role in regula...
Kisspeptin-Gpr54 signaling is critical for the GnRH neuronal network controlling fertility. The pres...
The gonadotropin-releasing hormone (GnRH) neurons are the principal neurons in a network within the ...
The gonadotropin-releasing hormone (GnRH) neurons are the principal neurons in a network within the ...
Kisspeptin neurons are critical components of the neuronal network controlling the activity of the g...
The neuropeptide kisspeptin is a potent stimulator of GnRH neurons and has been implicated as a majo...
Kisspeptin, encoded by Kiss1, stimulates GnRH neurons to govern reproduction. In rodents, estro-gen-...
Kisspeptin, encoded by Kiss1, stimulates GnRH neurons to govern reproduction. In rodents, estrogen-s...
Kisspeptin, encoded by Kiss1, stimulates GnRH neurons to govern reproduction. In rodents, estrogen-s...
Reproduction and fertility in mammals is critically dependent on the neurosecretion of gonadotrophin...
Reproduction and fertility in mammals is critically dependent on the neurosecretion of gonadotrophin...
Kisspeptin (encoded by Kiss1), a neuropeptide critically involved in neuroendocrine regulation of re...
Kisspeptin is a potent activator of GnRH-induced gonadotropin secretion and is a proposed central re...
The neuropeptide kisspeptin, encoded by Kiss1, regulates reproduction by stimulating GnRH secretion....
The neuropeptide kisspeptin, encoded by Kiss1, regulates reproduction by stimulating GnRH secretion....
It is now well established that the kisspeptin neurons of the hypothalamus play a key role in regula...