The suprachiasmatic nucleus (SCN)-often referred to as the master circadian clock-is essential in generating physiologic rhythms and orchestrating synchrony among circadian clocks. This study tested the hypothesis that periodic motivation induced by rhythmically pairing 2 reinforcing stimuli [methamphetamine (Meth) and running wheel (RW)] restores autonomous circadian activity in arrhythmic SCN-lesioned (SCNX) C3H/HeN mice. Sham-surgery and SCNX mice were treated with either Meth (1.2 mg/kg, i.p.) or vehicle in association, dissociation, or absence of an RW. Only the association of Meth treatment and restricted RW access successfully reestablished entrained circadian rhythms in mice with SCNX. RW-likely acting as a link between the circadia...
Sleep-wake cycling is controlled by the complex interplay between two brain systems, one which contr...
The suprachiasmatic nucleus (SCN) is a circadian oscillator that derives functional utility from its...
Circadian rhythms of behavior and physiology in rodents are regulated by a system of endogenous circ...
We investigated the effect of methamphetamine (MA) injections on the circadian organization of behav...
The dorsal striatum forms part of the basal ganglia circuit that is a major regulator of voluntary m...
<div><p>Circadian rhythms are regulated by the suprachiasmatic nucleus (SCN), a small structure at t...
Circadian rhythms are regulated by the suprachiasmatic nucleus (SCN), a small structure at the base ...
Using mice with disrupted neuropeptide signaling, Hughes et al. show that daily scheduled voluntary ...
AbstractThe mammalian master clock driving circadian rhythmicity in physiology and behavior resides ...
The suprachiasmatic nuclei (SCN) coordinate the daily sleep-wake cycle by generating a circadian rhy...
Color poster with text and graphs.Mice are nocturnal animals that exhibit predictable activity patte...
The suprachiasmatic nucleus (SCN) of the hypothalamus is a precise timekeeper that controls and sync...
SummaryIn mammals, the principal circadian pacemaker driving daily physiology and behavioral rhythms...
Circadian abnormalities seen in Huntington's disease (HD) patients are recapitulated in several HD t...
In mammals, daily rhythms in behavior and physiology are under control of an endogenous clock or pac...
Sleep-wake cycling is controlled by the complex interplay between two brain systems, one which contr...
The suprachiasmatic nucleus (SCN) is a circadian oscillator that derives functional utility from its...
Circadian rhythms of behavior and physiology in rodents are regulated by a system of endogenous circ...
We investigated the effect of methamphetamine (MA) injections on the circadian organization of behav...
The dorsal striatum forms part of the basal ganglia circuit that is a major regulator of voluntary m...
<div><p>Circadian rhythms are regulated by the suprachiasmatic nucleus (SCN), a small structure at t...
Circadian rhythms are regulated by the suprachiasmatic nucleus (SCN), a small structure at the base ...
Using mice with disrupted neuropeptide signaling, Hughes et al. show that daily scheduled voluntary ...
AbstractThe mammalian master clock driving circadian rhythmicity in physiology and behavior resides ...
The suprachiasmatic nuclei (SCN) coordinate the daily sleep-wake cycle by generating a circadian rhy...
Color poster with text and graphs.Mice are nocturnal animals that exhibit predictable activity patte...
The suprachiasmatic nucleus (SCN) of the hypothalamus is a precise timekeeper that controls and sync...
SummaryIn mammals, the principal circadian pacemaker driving daily physiology and behavioral rhythms...
Circadian abnormalities seen in Huntington's disease (HD) patients are recapitulated in several HD t...
In mammals, daily rhythms in behavior and physiology are under control of an endogenous clock or pac...
Sleep-wake cycling is controlled by the complex interplay between two brain systems, one which contr...
The suprachiasmatic nucleus (SCN) is a circadian oscillator that derives functional utility from its...
Circadian rhythms of behavior and physiology in rodents are regulated by a system of endogenous circ...