Pharmacokinetics of intraperitoneal cefalothin and cefazolin in patients being treated for peritoneal dialysis-associated peritonitis
- Roberts, Darren M.
- Ranganathan, Dwarakanathan
- Wallis, Steven C.
- Varghese, Julie M.
- Kark, Adrian
- Lipman, Jeffrey
- Roberts, Jason A.
Publication date
July 2016
DOI Publisher
MultiMed Inc. ISSN
0896-8608 Citation count (estimate)
1Abstract
Background: The standard treatment of peritoneal dialysis (PD)-associated peritonitis (PD-peritonitis) is intraperitoneal (IP) administration of antibiotics. Only limited data on the pharmacokinetics and appropriateness of contemporary dose recommendations of IP cefalothin and cefazolin exist. The aim of this study was to describe the pharmacokinetics of IP cefalothin and cefazolin in patients treated for PD-peritonitis
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