Add to ORKGBy means of immunohistochemical investigation, we have determined that in the sigmoid colon of diverticular disease patients there is a significant decrease in CGRP-IR nerve fibres (p<0,001). On the contrary, in diverticular disease patients, we found an increase in CGRP receptor, CRLR, expression within the enteric plexuses (p<0,01). These differences were most pronounced within the myenteric neural plexus, where CGRP was shown to have an intricate relationship with the nitriergic system and is known to be involved in colonic motor activity
Glial cell line-derived neurotrophic factor (GDNF) is a potent neurotrophic factor known to promote ...
The pattern of nerve cells and fibers containing calcitonin gene-related peptide immunoreactivity (C...
The definitive version is available at www.blackwell-synergy.comBackgroundInflammatory bowel disease...
The enteric nervous system (ENS), localized in the wall of the gastrointestinal tract, regulates the...
Calcitonin gene-related peptide (CGRP) exerts its diverse effects on vasodilation, nociception, secr...
Some patients with colonic diverticula suffer recurrent abdominal pain and exhibit visceral hypersen...
ABSTRACT Recently we demonstrated that sensory denervation with the neurotoxin capsaicin worsened th...
Clinical studies have suggested a link between the sensory trigeminal system and the parasympathetic...
of colonic specimens from patients with DD.The immunohistochemical analysis revealed significant ab...
The CGRP was localized immunohistochemically in neurons and fibres in lamb ileum wholemount preparat...
Absence of glial cell line-derived neurotrophic factor (GDNF) leads to intestinal aganglionosis. We ...
Colonic diverticular disease is a frequent finding in daily clinical practice. However, its pathophy...
Background: Colonic diverticulosis is a common condition in industrialized countries. Up to 25% of p...
<p>CGRP(+) nerve terminals were demonstrated by anti-CGRP antiserum on the lumbar cord sections and ...
The pathogenesis of diverticular disease (DD) is thought to result from complex interactions among d...
Glial cell line-derived neurotrophic factor (GDNF) is a potent neurotrophic factor known to promote ...
The pattern of nerve cells and fibers containing calcitonin gene-related peptide immunoreactivity (C...
The definitive version is available at www.blackwell-synergy.comBackgroundInflammatory bowel disease...
The enteric nervous system (ENS), localized in the wall of the gastrointestinal tract, regulates the...
Calcitonin gene-related peptide (CGRP) exerts its diverse effects on vasodilation, nociception, secr...
Some patients with colonic diverticula suffer recurrent abdominal pain and exhibit visceral hypersen...
ABSTRACT Recently we demonstrated that sensory denervation with the neurotoxin capsaicin worsened th...
Clinical studies have suggested a link between the sensory trigeminal system and the parasympathetic...
of colonic specimens from patients with DD.The immunohistochemical analysis revealed significant ab...
The CGRP was localized immunohistochemically in neurons and fibres in lamb ileum wholemount preparat...
Absence of glial cell line-derived neurotrophic factor (GDNF) leads to intestinal aganglionosis. We ...
Colonic diverticular disease is a frequent finding in daily clinical practice. However, its pathophy...
Background: Colonic diverticulosis is a common condition in industrialized countries. Up to 25% of p...
<p>CGRP(+) nerve terminals were demonstrated by anti-CGRP antiserum on the lumbar cord sections and ...
The pathogenesis of diverticular disease (DD) is thought to result from complex interactions among d...
Glial cell line-derived neurotrophic factor (GDNF) is a potent neurotrophic factor known to promote ...
The pattern of nerve cells and fibers containing calcitonin gene-related peptide immunoreactivity (C...
The definitive version is available at www.blackwell-synergy.comBackgroundInflammatory bowel disease...