Automatic segmentation of myocardium at risk from contrast enhanced SSFP CMR: validation against expert readers and SPECT.
- Tufvesson, Jane
- Carlsson, Marcus
- Aletras, Anthony
- Engblom, Henrik
- Deux, Jean-François
- Koul, Sasha
- Sörensson, Peder
- Pernow, John
- Atar, Dan
- Erlinge, David
- Arheden, Håkan
- Heiberg, Einar
Publication date
January 2016
DOI Publisher
Springer Science and Business Media LLC ISSN
1532-429XAbstract
Efficacy of reperfusion therapy can be assessed as myocardial salvage index (MSI) by determining the size of myocardium at risk (MaR) and myocardial infarction (MI), (MSI = 1-MI/MaR). Cardiovascular magnetic resonance (CMR) can be used to assess MI by late gadolinium enhancement (LGE) and MaR by either T2-weighted imaging or contrast enhanced SSFP (CE-SSFP). Automatic segmentation algorithms have been developed and validated for MI by LGE as well as for MaR by T2-weighted imaging. There are, however, no algorithms available for CE-SSFP. Therefore, the aim of this study was to develop and validate automatic segmentation of MaR in CE-SSFP
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