Objectives: The benefits of PSA (prostate specific antigen)-testing in prostate cancer remain controversial with a consequential need for validation of additional biomarkers. We used highly standardized reverse-transcription (RT)-PCR assays to compare transcript levels of 10 candidate cancer marker genes - BMP6, FGF-8b, KLK2, KLK3, KLK4, KLK15, MSMB, PCA3, PSCA and Trpm8 - in carefully ascertained non-cancerous versus cancerous prostate tissue from patients with clinically localized prostate cancer treated by radical prostatectomy. Design and methods: Total RNA was isolated from fresh frozen prostate tissue procured immediately after resection from two separate areas in each of 87 radical prostatectomy specimens. Subsequent histopathologica...
Background: Knowledge of preanalytic conditions that biospecimens are subjected to is critically imp...
Background: Molecular signatures in prostate cancer (PCa) tissue can provide useful prognostic infor...
[[abstract]]Prostate cancer (PCa) is the second-leading cause of cancer death among men in the world...
Background: The aim of the study was to evaluate the diagnostic power of molecular markers in men wi...
Background: The aim of the study was to evaluate the diagnostic power of molecular markers in men wi...
Prostate-specific antigen (PSA) is important in tumour detection, monitoring disease progression and...
Currently, no ideal prostate cancer (PCa) diagnostic or prognostic test is available due to the lack...
Serum PSA has shown to be the most valuable tool in the detection, staging and monitoring of prostat...
Prostate cancer (PCa) is the most common cancer in men. It is a heterogeneous disease and currently ...
Purpose: The diagnosis of prostate cancer in men with persistently increased prostate specific antig...
Biomarkers are important for early detection of cancer, prognosis, response prediction, and detectio...
Contains fulltext : 81148schalken.pdf (publisher's version ) (Closed access)Althou...
Background Prostate tumor heterogeneity and biopsy undersampling pose challenges to accurate, indivi...
PURPOSE: Serum PSA (sPSA) testing has led to the identification of patients with indolent prostate c...
The occurence of prostate cancer (PCa) has been consistently rising since three decades and remains ...
Background: Knowledge of preanalytic conditions that biospecimens are subjected to is critically imp...
Background: Molecular signatures in prostate cancer (PCa) tissue can provide useful prognostic infor...
[[abstract]]Prostate cancer (PCa) is the second-leading cause of cancer death among men in the world...
Background: The aim of the study was to evaluate the diagnostic power of molecular markers in men wi...
Background: The aim of the study was to evaluate the diagnostic power of molecular markers in men wi...
Prostate-specific antigen (PSA) is important in tumour detection, monitoring disease progression and...
Currently, no ideal prostate cancer (PCa) diagnostic or prognostic test is available due to the lack...
Serum PSA has shown to be the most valuable tool in the detection, staging and monitoring of prostat...
Prostate cancer (PCa) is the most common cancer in men. It is a heterogeneous disease and currently ...
Purpose: The diagnosis of prostate cancer in men with persistently increased prostate specific antig...
Biomarkers are important for early detection of cancer, prognosis, response prediction, and detectio...
Contains fulltext : 81148schalken.pdf (publisher's version ) (Closed access)Althou...
Background Prostate tumor heterogeneity and biopsy undersampling pose challenges to accurate, indivi...
PURPOSE: Serum PSA (sPSA) testing has led to the identification of patients with indolent prostate c...
The occurence of prostate cancer (PCa) has been consistently rising since three decades and remains ...
Background: Knowledge of preanalytic conditions that biospecimens are subjected to is critically imp...
Background: Molecular signatures in prostate cancer (PCa) tissue can provide useful prognostic infor...
[[abstract]]Prostate cancer (PCa) is the second-leading cause of cancer death among men in the world...