TCF7L2 type 2 diabetes risk variant, lifestyle factors, and incidence of prostate cancer.
- Drake, Isabel
- Wallström, Peter
- Hindy, George
- Ericson, Ulrika
- Gullberg, Bo
- Bjartell, Anders
- Sonestedt, Emily
- Orho-Melander, Marju
- Wirfält, Elisabet
Publication date
January 2014
DOI Publisher
Wiley ISSN
0270-4137 Citation count (estimate)
4Abstract
Variation in transcription factor 7-like 2 (TCF7L2), the strongest genetic risk factor for type 2 diabetes (T2D), may play a role in prostate cancer (PCa) depending on lifestyle factors. The aims of this study were to determine if TCF7L2 rs7903146 is associated with risk of PCa and if the association is modified by lifestyle factors independently of T2D status
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