As a redhead I have had a personal interest in red hair, freckles and sunburns since childhood. An observation of a formaldehyde-induced fluorescence in human epidermal melanocytes initiated my scientific interest in these cells. Prota and Nicolaus demonstrated that oxidation products of cysteinyldopas are the main components of pheomelanin. Our identification of 5-S-cysteinyldopa as the source of formaldehyde-induced fluorescence of normal and pathological melanocytes started a series of investigations into this amino acid, enzymatic and non-enzymatic oxidation of catecholic compounds and the metabolism of thiols. All melanocytes with functioning tyrosinase produce cysteinyldopas and the levels of 5-S-cysteinyldopa in serum and urine are r...
Three different groups of chemical intermediates are known to be formed during the synthesis of mela...
The aim of the present work was to estimate the effect of intracellular glutathione depletion on mel...
Determination of urine cysteinyldopa excretion is the most sensitive chemical test for the detection...
Recent evidence suggests that the melanogenesis intermediate 5-S-cysteinyldopa (5-S-CD) could displa...
5-S-Cysteinyldopa (5-S-CD) is found in all pigment-producing cells and is the major precursor of pha...
The catechol 5-S-cysteinyldopa (5-S-CD) is produced in large amounts in metastatic malignant melanom...
Interest in 5-S-cysteinyldopa (5-S-CD), a major excretion product of normal and malignant melanocyte...
Interest in 5-S-cysteinyldopa (5-S-CD), a major excretion product of normal and malignant melanocyte...
Interest in 5-S-cysteinyldopa (5-S-CD), a major excretion product of normal and malignant melanocyte...
Interest in 5-S-cysteinyldopa (5-S-CD), a major excretion product of normal and malignant melanocyte...
The color of mammalian hair, skin, and eyes results mainly from the secretory products of melanocyte...
Conjugates of phenols with biological thiols have recently received increasing interest because of t...
Conjugates of phenols with biological thiols have recently received increasing interest because of t...
Conjugates of phenols with biological thiols have recently received increasing interest because of t...
The distribution of γ-glutamyl transpeptidase (γ-GTP), tyrosinase, and 5-S-cysteinyldopa (5-S-CD) wi...
Three different groups of chemical intermediates are known to be formed during the synthesis of mela...
The aim of the present work was to estimate the effect of intracellular glutathione depletion on mel...
Determination of urine cysteinyldopa excretion is the most sensitive chemical test for the detection...
Recent evidence suggests that the melanogenesis intermediate 5-S-cysteinyldopa (5-S-CD) could displa...
5-S-Cysteinyldopa (5-S-CD) is found in all pigment-producing cells and is the major precursor of pha...
The catechol 5-S-cysteinyldopa (5-S-CD) is produced in large amounts in metastatic malignant melanom...
Interest in 5-S-cysteinyldopa (5-S-CD), a major excretion product of normal and malignant melanocyte...
Interest in 5-S-cysteinyldopa (5-S-CD), a major excretion product of normal and malignant melanocyte...
Interest in 5-S-cysteinyldopa (5-S-CD), a major excretion product of normal and malignant melanocyte...
Interest in 5-S-cysteinyldopa (5-S-CD), a major excretion product of normal and malignant melanocyte...
The color of mammalian hair, skin, and eyes results mainly from the secretory products of melanocyte...
Conjugates of phenols with biological thiols have recently received increasing interest because of t...
Conjugates of phenols with biological thiols have recently received increasing interest because of t...
Conjugates of phenols with biological thiols have recently received increasing interest because of t...
The distribution of γ-glutamyl transpeptidase (γ-GTP), tyrosinase, and 5-S-cysteinyldopa (5-S-CD) wi...
Three different groups of chemical intermediates are known to be formed during the synthesis of mela...
The aim of the present work was to estimate the effect of intracellular glutathione depletion on mel...
Determination of urine cysteinyldopa excretion is the most sensitive chemical test for the detection...