Intensified Tuberculosis Case-Finding in HIV-Positive Adults Managed at Ethiopian Health Centers: Diagnostic Yield of Xpert MTB/RIF Compared with Smear Microscopy and Liquid Culture.
- Balcha, Taye
- Sturegård, Erik
- Winqvist, Niclas
- Skogmar, Sten
- Reepalu, Anton
- Jemal, Zelalem Habtamu
- Tibesso, Gudeta
- Schön, Thomas
- Björkman, Per
Publication date
January 2014
DOI Publisher
Public Library of Science (PLoS)Abstract
Detection of active tuberculosis (TB) before antiretroviral therapy (ART) initiation is important, but optimal diagnostic methods for use in resource-limited settings are lacking. We assessed the prevalence of TB, evaluated the diagnostic yield of Xpert MTB/RIF in comparison with smear microscopy and culture, and the impact of Xpert results on clinical management in HIV-positive adults eligible for ART at health centers in a region of Ethiopia
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