Acute rheumatic fever (ARF) and acute poststreptococcal glomerulonephritis (APSGN), two important sequelae of streptococcal throat or skin infections, according to current concepts may be elicited by autoimmune mechanisms due to molecular mimicry between group A streptococci (GAS) and human tissue. In the case of APSGN, however, Our experimental data have indicated that GAS immunoglobulin-binding surface proteins (IgG Bps) might be of pathogenic significance by triggering anti-IgG production and immune complex formation leading to renal damage. Thus, rabbits injected with IEG-binding, as opposed to non-binding, GAS strains were found to develop renal deposition of IgG and complement factor C3 and inflammatory and degenerative glomerular cha...
The aim of present study was to arrange an experimental rabbit model for IgA-nephropathy. To this pu...
Acute rheumatic fever (ARF) and rheumatic heart disease (RHD) are autoimmune mediated diseases cause...
Acute rheumatic fever (ARF) and rheumatic heart disease (RHD) are autoimmune sequelae of upper res-p...
Background & objectives: We have earlier proposed that group A streptococcal (GAS) immunoglobulin bi...
Our previous studies have indicated that the IgG-binding M-family proteins (IgGBP) of group A strept...
Acute rheumatic fever and rheumatic heart disease (ARF/RHD) have long been described as autoimmune s...
Acute rheumatic fever and rheumatic heart disease (ARF/RHD) have long been described as autoimmune s...
In a rabbit model, we have previously reported evidence for a pathogenic role of streptococcal IgG F...
Acute rheumatic fever and rheumatic heart disease (ARF/RHD) have long been described as autoimmune s...
Rheumatic fever and rheumatic heart disease (RF/RHD) develop following repeated infection with group...
Acute Rheumatic Fever and Rheumatic Heart Disease (ARF/RHD) are triggered by an autoimmune response...
Rheumatic fever (RF) and rheumatic heart disease (RHD) are sequelae of group A streptococcal (GAS) i...
Acute rheumatic fever (ARF) and rheumatic heart disease (RHD) are autoimmune mediated diseases trigg...
Acute rheumatic fever and rheumatic heart disease (ARF/RHD) have long been described as autoimmune s...
The etiology of rheumatic fever and rheumatic heart disease (RF/RHD) is believed to be autoimmune, i...
The aim of present study was to arrange an experimental rabbit model for IgA-nephropathy. To this pu...
Acute rheumatic fever (ARF) and rheumatic heart disease (RHD) are autoimmune mediated diseases cause...
Acute rheumatic fever (ARF) and rheumatic heart disease (RHD) are autoimmune sequelae of upper res-p...
Background & objectives: We have earlier proposed that group A streptococcal (GAS) immunoglobulin bi...
Our previous studies have indicated that the IgG-binding M-family proteins (IgGBP) of group A strept...
Acute rheumatic fever and rheumatic heart disease (ARF/RHD) have long been described as autoimmune s...
Acute rheumatic fever and rheumatic heart disease (ARF/RHD) have long been described as autoimmune s...
In a rabbit model, we have previously reported evidence for a pathogenic role of streptococcal IgG F...
Acute rheumatic fever and rheumatic heart disease (ARF/RHD) have long been described as autoimmune s...
Rheumatic fever and rheumatic heart disease (RF/RHD) develop following repeated infection with group...
Acute Rheumatic Fever and Rheumatic Heart Disease (ARF/RHD) are triggered by an autoimmune response...
Rheumatic fever (RF) and rheumatic heart disease (RHD) are sequelae of group A streptococcal (GAS) i...
Acute rheumatic fever (ARF) and rheumatic heart disease (RHD) are autoimmune mediated diseases trigg...
Acute rheumatic fever and rheumatic heart disease (ARF/RHD) have long been described as autoimmune s...
The etiology of rheumatic fever and rheumatic heart disease (RF/RHD) is believed to be autoimmune, i...
The aim of present study was to arrange an experimental rabbit model for IgA-nephropathy. To this pu...
Acute rheumatic fever (ARF) and rheumatic heart disease (RHD) are autoimmune mediated diseases cause...
Acute rheumatic fever (ARF) and rheumatic heart disease (RHD) are autoimmune sequelae of upper res-p...