CD8+ T cell activation predominate early immune responses to hypercholesterolemia in Apoe-/- mice.
- Kolbus, Daniel
- Ramos, Ornélia
- Berg, Katarina
- Persson, Josefin
- Wigren, Maria
- Björkbacka, Harry
- Nordin Fredrikson, Gunilla
- Nilsson, Jan
Publication date
January 2010
DOI Publisher
Springer Science and Business Media LLCAbstract
It is well established that adaptive immune responses induced by hypercholesterolemia play an important role in the development of atherosclerosis, but the pathways involved remain to be fully characterized. In the present study we assessed immune responses to hypercholesterolemia induced by feeding Apoe-/- mice a high-fat diet for 4 or 8 weeks
Add to ORKG