The DEK oncoprotein binds to highly and ubiquitously expressed genes with a dual role in their transcriptional regulation.
- Sandén, Carl
- Järvstråt, Linnea
- Lennartsson, Andreas
- Brattaas, Per Ludvik
- Nilsson, Björn
- Gullberg, Urban
Publication date
January 2014
DOI Publisher
Springer Science and Business Media LLCAbstract
The DEK gene is highly expressed in a wide range of cancer cells, and a recurrent translocation partner in acute myeloid leukemia. While DEK has been identified as one of the most abundant proteins in human chromatin, its function and binding properties are not fully understood
Add to ORKG