Sex-Specific Effects of Adiponectin on Carotid Intima-Media Thickness and Incident Cardiovascular Disease.
- Persson, Jonas
- Strawbridge, Rona J
- McLeod, Olga
- Gertow, Karl
- Silveira, Angela
- Baldassarre, Damiano
- Van Zuydam, Natalie
- Shah, Sonia
- Fava, Cristiano
- Gustafsson, Stefan
- Veglia, Fabrizio
- Sennblad, Bengt
- Larsson, Malin
- Sabater-Lleal, Maria
- Leander, Karin
- Gigante, Bruna
- Tabak, Adam
- Kivimaki, Mika
- Kauhanen, Jussi
- Rauramaa, Rainer
- Smit, Andries J
- Mannarino, Elmo
- Giral, Philippe
- Humphries, Steve E
- Tremoli, Elena
- de Faire, Ulf
- Lind, Lars
- Ingelsson, Erik
- Hedblad, Bo
- Melander, Olle
- Kumari, Meena
- Hingorani, Aroon
- Morris, Andrew D
- Palmer, Colin N A
- Lundman, Pia
- Öhrvik, John
- Söderberg, Stefan
- Hamsten, Anders
Publication date
January 2015
DOI Publisher
Ovid Technologies (Wolters Kluwer Health)Abstract
Plasma adiponectin levels have previously been inversely associated with carotid intima-media thickness (IMT), a marker of subclinical atherosclerosis. In this study, we used a sex-stratified Mendelian randomization approach to investigate whether adiponectin has a causal protective influence on IMT
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