BACKGROUND: The minor T allele of rs2943641 near the gene encoding for insulin receptor substrate 1 (IRS1) has been associated with decreased risk of type 2 diabetes (T2D) and adiposity in genome-wide association studies. Dietary intake can influence the regulation of IRS1, and studies have indicated sex-specific associations between IRS1 and adiposity. OBJECTIVE: The objective was to examine the interaction between IRS1 rs2943641 and macronutrient intakes on incident T2D and percentage body fat in the Malmö Diet and Cancer cohort. DESIGN: The study included 15,227 women and 9614 men aged 45-74 y without prevalent diabetes. Dietary data were collected with a modified diet history method. During 12 y follow-up, 1567 incident T2D cases were i...
Insulin receptor substrate 1 (IRS1), plays a critical role in insulin signaling and its control has ...
To investigate the role of IRS1 locus on failure to oral antidiabetes drugs (OADs) we genotyped sing...
The gene encoding insulin receptor substrate-1 (IRS1) represents a strong biological candidate for a...
AbstractBackground and aimsA recent genome-wide association study identified rs2943641C > T, 500 kb ...
The insulin receptor substrate-1 (IRS1) plays an important role in insulin signaling. A recent genom...
Anas A Yousef,1 Eman G Behiry,1 Wafaa M Abd Allah,1 Ahmed M Hussien,2 Abdelmoneam A Abdelmoneam,2 Ma...
AIMS: The insulin receptor substrate-1 (IRS-1) gene is among the most frequently studied candidate g...
Genome-wide association studies have identified common variants that only partially explain the gene...
Aims: The insulin receptor substrate-1 (IRS-1) gene is among the most frequently studied candidate g...
Background—Common genetic variants in the insulin receptor substrate 1 (IRS1) gene have been recentl...
Objective: SNP rs2943641 near the insulin receptor substrate 1 (IRS1) gene has been found to be asso...
A recent genome-wide association study identified rs2943641C > T, 500 kb from the insulin receptor s...
Insulin receptor substrate-2 (IRS-2), one of the major substrates of the insulin receptor, has a cru...
Objective: Published data concerning associations between IRS1 variants and type 2 diabetes and rela...
Background and Objectives: The insulin receptor substrate-1 (IRS1) gene is a candidate gene for type...
Insulin receptor substrate 1 (IRS1), plays a critical role in insulin signaling and its control has ...
To investigate the role of IRS1 locus on failure to oral antidiabetes drugs (OADs) we genotyped sing...
The gene encoding insulin receptor substrate-1 (IRS1) represents a strong biological candidate for a...
AbstractBackground and aimsA recent genome-wide association study identified rs2943641C > T, 500 kb ...
The insulin receptor substrate-1 (IRS1) plays an important role in insulin signaling. A recent genom...
Anas A Yousef,1 Eman G Behiry,1 Wafaa M Abd Allah,1 Ahmed M Hussien,2 Abdelmoneam A Abdelmoneam,2 Ma...
AIMS: The insulin receptor substrate-1 (IRS-1) gene is among the most frequently studied candidate g...
Genome-wide association studies have identified common variants that only partially explain the gene...
Aims: The insulin receptor substrate-1 (IRS-1) gene is among the most frequently studied candidate g...
Background—Common genetic variants in the insulin receptor substrate 1 (IRS1) gene have been recentl...
Objective: SNP rs2943641 near the insulin receptor substrate 1 (IRS1) gene has been found to be asso...
A recent genome-wide association study identified rs2943641C > T, 500 kb from the insulin receptor s...
Insulin receptor substrate-2 (IRS-2), one of the major substrates of the insulin receptor, has a cru...
Objective: Published data concerning associations between IRS1 variants and type 2 diabetes and rela...
Background and Objectives: The insulin receptor substrate-1 (IRS1) gene is a candidate gene for type...
Insulin receptor substrate 1 (IRS1), plays a critical role in insulin signaling and its control has ...
To investigate the role of IRS1 locus on failure to oral antidiabetes drugs (OADs) we genotyped sing...
The gene encoding insulin receptor substrate-1 (IRS1) represents a strong biological candidate for a...