Add to ORKGA streamlined strategy was developed to obtain a mixture of thapsigargins from the fruits of Thapsia garganica L. The mixture was resolved by RP-silica gel flash chromatography to provide, after trituration with ether, 0.32% thapsigargin (la) as a white powder. A novel, complex phenylpropanoid (neohelmanthicin D, 2a) was also obtained, and its structure confirmed by semisynthesis
In natural products research, the efficient purification of molecules from large amount of complex e...
Introduction - Asparagus officinalis L. has several biological activities including antifungal, anti...
The leaves of Leucosidea sericea (Rosaceae) are used medicinally by some indigenous South African pe...
A streamlined strategy was developed to obtain a mixture of thapsigargins from the fruits of Thapsia...
An investigation of Thapsia garganica afforded a series of tetracyclic C-19 dilactones, whose produc...
The sesquiterpene lactone thapsigargin is found in the plant Thapsia garganica L., and is one of the...
Herein we describe the total synthesis of five guaianolide natural products: thapsigargin, thapsivil...
The thapsigargins are a family of complex guaianolides with potent and selective Ca(2+)-modulating p...
Chapter one presents an account of the isolation and structure determination of thapsigargin and rel...
An analysis of the binding of the 8 O N tert butoxycarbonyl 12 aminododecanoyl derivative of 8 O deb...
Since cells in solid tumors divide less rapidly than cells in the bone marrow or cells of the immune...
Analysis of molecular interaction fields based on the published crystal structure of thapsigargin bo...
In 2005 two research groups independently reported the isolation of a series of structurally intrigu...
An entirely substrate-controlled total synthesis of three members of the thapsigargin family (e.g. t...
The plant Psychotria kirkii hosts an obligatory bacterial symbiont, Candidatus Burkholderia kirkii, ...
In natural products research, the efficient purification of molecules from large amount of complex e...
Introduction - Asparagus officinalis L. has several biological activities including antifungal, anti...
The leaves of Leucosidea sericea (Rosaceae) are used medicinally by some indigenous South African pe...
A streamlined strategy was developed to obtain a mixture of thapsigargins from the fruits of Thapsia...
An investigation of Thapsia garganica afforded a series of tetracyclic C-19 dilactones, whose produc...
The sesquiterpene lactone thapsigargin is found in the plant Thapsia garganica L., and is one of the...
Herein we describe the total synthesis of five guaianolide natural products: thapsigargin, thapsivil...
The thapsigargins are a family of complex guaianolides with potent and selective Ca(2+)-modulating p...
Chapter one presents an account of the isolation and structure determination of thapsigargin and rel...
An analysis of the binding of the 8 O N tert butoxycarbonyl 12 aminododecanoyl derivative of 8 O deb...
Since cells in solid tumors divide less rapidly than cells in the bone marrow or cells of the immune...
Analysis of molecular interaction fields based on the published crystal structure of thapsigargin bo...
In 2005 two research groups independently reported the isolation of a series of structurally intrigu...
An entirely substrate-controlled total synthesis of three members of the thapsigargin family (e.g. t...
The plant Psychotria kirkii hosts an obligatory bacterial symbiont, Candidatus Burkholderia kirkii, ...
In natural products research, the efficient purification of molecules from large amount of complex e...
Introduction - Asparagus officinalis L. has several biological activities including antifungal, anti...
The leaves of Leucosidea sericea (Rosaceae) are used medicinally by some indigenous South African pe...