Identification and characterization of leukemia-initiating cells (LICs) is important to understand leukemogenesis and develop novel therapies for leukemia. In this issue of Cell Stem Cell, Gibbs et al. (2012) demonstrate that common active signaling pathways in LICs may be targeted to treat acute myeloid leukemia
Acute myeloid leukemia (AML) is a disorder of the hematopoietic system in which there is an overprod...
Leukemic stem cells (LSCs) in acute myeloid leukemia (AML) represent a low-frequency subpopulation o...
Notch signaling pathway regulates many different events of embryonic and adult development: among th...
Identification and characterization of leukemia-initiating cells (LICs) is important to understand l...
Disease relapse remains the major clinical challenge in treating T-cell acute lymphoblastic leukemia...
Acute myeloid leukemia (AML) is one of the most common types of leukemia in adults. While complete r...
Stem cells are an integral component of normal mammalian physiology and have been intensively studie...
Since the discovery of leukemic stem cells (LSCs) over a decade ago, many of their critical biologic...
Leukemia initiating cells (LICs) represent a reservoir that is believed to drive relapse and resista...
Leukemia initiating cells (LICs) represent a reservoir that is believed to drive relapse and resista...
Acute myeloid leukemia (AML) is an aggressive malignancy with a-5 year overall survival rate of appr...
Despite recent advances, treatment of leukemia is often not curative. New insights indicate that thi...
INTRODUCTION: Treatment failure in acute myeloid leukemia is probably caused by the presence of leuk...
Acute myeloid leukemia (AML) is the most frequent leukemia in adults and presents a very high incide...
Identification of tractable signaling molecules essential for leukemogenesis facilitates the develop...
Acute myeloid leukemia (AML) is a disorder of the hematopoietic system in which there is an overprod...
Leukemic stem cells (LSCs) in acute myeloid leukemia (AML) represent a low-frequency subpopulation o...
Notch signaling pathway regulates many different events of embryonic and adult development: among th...
Identification and characterization of leukemia-initiating cells (LICs) is important to understand l...
Disease relapse remains the major clinical challenge in treating T-cell acute lymphoblastic leukemia...
Acute myeloid leukemia (AML) is one of the most common types of leukemia in adults. While complete r...
Stem cells are an integral component of normal mammalian physiology and have been intensively studie...
Since the discovery of leukemic stem cells (LSCs) over a decade ago, many of their critical biologic...
Leukemia initiating cells (LICs) represent a reservoir that is believed to drive relapse and resista...
Leukemia initiating cells (LICs) represent a reservoir that is believed to drive relapse and resista...
Acute myeloid leukemia (AML) is an aggressive malignancy with a-5 year overall survival rate of appr...
Despite recent advances, treatment of leukemia is often not curative. New insights indicate that thi...
INTRODUCTION: Treatment failure in acute myeloid leukemia is probably caused by the presence of leuk...
Acute myeloid leukemia (AML) is the most frequent leukemia in adults and presents a very high incide...
Identification of tractable signaling molecules essential for leukemogenesis facilitates the develop...
Acute myeloid leukemia (AML) is a disorder of the hematopoietic system in which there is an overprod...
Leukemic stem cells (LSCs) in acute myeloid leukemia (AML) represent a low-frequency subpopulation o...
Notch signaling pathway regulates many different events of embryonic and adult development: among th...
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