Frequency and predictors of acute ischaemic lesions on brain magnetic resonance imaging in young patients with a clinical diagnosis of transient ischaemic attack

Tanislav, C
Grittner, U
Fazekas, F
Thijs, V
Tatlisumak, T
Huber, R
von Sarnowski, B
Putaala, J
Schmidt, R
Kropp, P
Norrving, B
Martus, P
Gramsch, C
Giese, A K
Rolfs, A
Enzinger, C

Open link

Publication date

July 2016

DOI

10.1111/ene.13012

Publisher

Wiley-Blackwell

ISSN

1351-5101

Citation count (estimate)

Abstract

BACKGROUND AND PURPOSE: Acute lesions in patients with transient ischaemic attack (TIA) are important as they are associated with increased risk for recurrence. Characteristics associated with acute lesions in young TIA patients were therefore investigated.METHODS: The sifap1 study prospectively recruited a multinational European cohort (n = 5023) of patients aged 18-55 years with acute cerebrovascular event. The detection of acute ischaemic lesions was based on diffusion-weighted imaging (DWI). The frequency of DWI lesions was assessed in 829 TIA patients who met the criteria of symptom duration <24 h and their association with demographic, clinical and imaging variables was analysed.RESULTS: The median age was 46 years (interquartile rang...