Mesenchymal stromal cells (MSC) are multipotent cells with regenerative and immune-modulatory properties. Therefore, MSC have been proposed as a potential cell-therapy for bronchiolitis obliterans syndrome (BOS). On the other hand, there are publications demonstrating that MSC might be involved in the development of BOS. Despite limited knowledge regarding the functional role of tissue-resident lung-MSC, several clinical trials have been performed using MSC, particularly bone marrow (BM)-derived MSC, for various lung diseases. We aimed to compare lung-MSC with the well-characterized BM-MSC. Furthermore, MSC isolated from lung-transplanted patients with BOS were compared to patients without BOS. Our study show that lung-MSCs are smaller, pos...
Stromal support is critical for lung homeostasis and the maintenance of an effective epithelial barr...
Background: Bronchiolitis obliterans syndrome (BOS) often develops in transplant patients and result...
Background: Mesenchymal stem cell (MSC) effects can shift immune responses toward anti-inflammatory ...
Mesenchymal stromal cells (MSC) are multipotent cells with regenerative and immune-modulatory proper...
Mesenchymal stromal cells (MSC) are multipotent cells with immunomodulatory and regenerative propert...
Obliterative bronchiolitis (OB) is a significant cause of morbidity and mortality after lung transpl...
BACKGROUND: Mesenchymal stem cells (MSC) have not only been implicated in the development of lung di...
Rationale: Obliterative bronchiolitis (OB) is a significant cause of morbidity and mortality after l...
Mesenchymal stromal cells (MSCs) reside in many organs including lung, as shown by their isolation f...
To date, bone marrow-derived mesenchymal stromal cells (MSCs) have been considered the golden standa...
Mesenchymal stem cells (MSC) have not only been implicated in the development of lung diseases, but ...
Lung diseases are among the most devastating illnesses because of their prevalence and simultaneous ...
AbstractAccumulating studies, both in animals and human clinical trials with mesenchymal stroma cell...
Bone marrow-derived mesenchymal stem cells (BMSCs) can ameliorate a variety of lung diseases such as...
Stem cells have been identified in the human lung; however, their role in lung disease is not clear....
Stromal support is critical for lung homeostasis and the maintenance of an effective epithelial barr...
Background: Bronchiolitis obliterans syndrome (BOS) often develops in transplant patients and result...
Background: Mesenchymal stem cell (MSC) effects can shift immune responses toward anti-inflammatory ...
Mesenchymal stromal cells (MSC) are multipotent cells with regenerative and immune-modulatory proper...
Mesenchymal stromal cells (MSC) are multipotent cells with immunomodulatory and regenerative propert...
Obliterative bronchiolitis (OB) is a significant cause of morbidity and mortality after lung transpl...
BACKGROUND: Mesenchymal stem cells (MSC) have not only been implicated in the development of lung di...
Rationale: Obliterative bronchiolitis (OB) is a significant cause of morbidity and mortality after l...
Mesenchymal stromal cells (MSCs) reside in many organs including lung, as shown by their isolation f...
To date, bone marrow-derived mesenchymal stromal cells (MSCs) have been considered the golden standa...
Mesenchymal stem cells (MSC) have not only been implicated in the development of lung diseases, but ...
Lung diseases are among the most devastating illnesses because of their prevalence and simultaneous ...
AbstractAccumulating studies, both in animals and human clinical trials with mesenchymal stroma cell...
Bone marrow-derived mesenchymal stem cells (BMSCs) can ameliorate a variety of lung diseases such as...
Stem cells have been identified in the human lung; however, their role in lung disease is not clear....
Stromal support is critical for lung homeostasis and the maintenance of an effective epithelial barr...
Background: Bronchiolitis obliterans syndrome (BOS) often develops in transplant patients and result...
Background: Mesenchymal stem cell (MSC) effects can shift immune responses toward anti-inflammatory ...