Ultrasound is at least as good as magnetic resonance imaging in predicting tumour size post-neoadjuvant chemotherapy in breast cancer
- Vriens, B.E.
- Vries, B. de
- Lobbes, M.B.
- Gastel, S.M. van
- Berkmortel, F.W. van den
- Smilde, T.J.
- Warmerdam, L.J. van
- Boer, M. de
- Spronsen, D.J. van
- Smidt, M.L.
- Peer, P.G.
- Aarts, M.J.
- Tjan-Heijnen, V.C.
DOIAbstract
Item does not contain fulltextBACKGROUND: The aim of this study was to evaluate the accuracy of clinical imaging of the primary breast tumour post-neoadjuvant chemotherapy (NAC) related to the post-neoadjuvant histological tumour size (gold standard) and whether this varies with breast cancer subtype. In this study, results of both magnetic resonance imaging (MRI) and ultrasound (US) were reported. METHODS: Patients with invasive breast cancer were enrolled in the INTENS study between 2006 and 2009. We included 182 patients, of whom data were available for post-NAC MRI (n=155), US (n=123), and histopathological tumour size. RESULTS: MRI estimated residual tumour size with <10-mm discordance in 54% of patients, overestimated size in 28% and ...
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