Osteophilic properties of bone implant surface modifications in a cassette model on a decorticated goat spinal transverse process
- Oirschot, B.A.J.A. van
- Eman, R.M.
- Habibovic, P.
- Leeuwenburgh, S.C.
- Tahmasebi, Z.
- Weinans, H.
- Alblas, J.
- Meijer, G.J.
- Jansen, J.A.
- Beucken, J.J.J.P van den
DOIAbstract
Item does not contain fulltextThis study comparatively evaluated the osteophilic capacity of 17 different surface modifications (i.e. fourteen different chemical modifications via ceramic coatings and three different physical modifications via surface roughness) for titanium (Ti) surfaces. All surface modifications were subjected to physico-chemical analyses and immersion in simulated body fluid (SBF) for coating stability assessment. Subsequently, a bone conduction chamber cassette model on the goat transverse process was used for comparative in vivo analysis based on bone responses to these different surface modifications after twelve weeks. Histological and histomorphometrical analyses in terms of longitudinal bone-to-implant contact per...
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