Roux-en-Y gastric bypass (RYGB) surgery induces various metabolic benefits in severely obese (BMI> 40 kg/m2) individuals, including improved insulin action in peripheral tissues, most notably skeletal muscle, and remission of type 2 diabetes. Despite these improvements, the mechanism in which RYGB improves metabolism is unclear. To examine this, primary human skeletal muscle cells were isolated from muscle biopsies obtained from individuals prior to, 1-month, and 7-months following RYGB. Insulin-stimulated glycogen synthesis, an index of insulin action, improved in myotubes derived from subjects at 1-month following RYGB, which was sustained at 7-months post-surgery. The cellular mechanisms involved appear to consist of distinct acute and c...
Aim. Bariatric surgery improves insulin sensitivity and glucose tolerance in obese individuals with ...
Skeletal muscle displays an extensive capacity to adapt to a wide range of metabolic and mechanical ...
Visceral adipose tissue (VAT) is associated with cardiometabolic risk factors and insulin resistance...
Roux-en-Y gastric bypass (RYGB) surgery induces various metabolic benefits in severely obese (BMI>...
BACKGROUND: Roux-en-Y gastric bypass (RYGB) surgery has been shown to induce positive metabolic adap...
Mitochondrial dynamics including mitochondrial fission (e.g., Dynamin-related protein 1 (Drp1) and F...
BACKGROUND: A large body of literature indicates the rapidity with which Roux-en-Y gastric bypass (R...
The Roux-en-Y gastric bypass (RYGB) is highly effective in the remission of obesity and associated d...
Severe obesity and Type 2 Diabetes (T2DM) are worldwide health concerns reaching epidemic proportion...
Skeletal muscle is the site at which highly regulated energetic processes take place as a means of m...
IntroductionRoux-en-Y gastric bypass (RYGB) is an effective treatment for type 2 diabetes mellitus (...
Context: Surgical treatments of obesity have been shown to induce rapid and prolonged improvements i...
Roux-en-Y gastric bypass (RYGB) is an effective method to attain sustained weight loss and diabetes ...
It has been shown that Type 2 diabetic patients who undergo Roux-en-Y Gastric Bypass surgery (RYGB) ...
The skeletal muscle of severely obese individuals (BMI > 40 kg/m²) is characterized by a depressed ...
Aim. Bariatric surgery improves insulin sensitivity and glucose tolerance in obese individuals with ...
Skeletal muscle displays an extensive capacity to adapt to a wide range of metabolic and mechanical ...
Visceral adipose tissue (VAT) is associated with cardiometabolic risk factors and insulin resistance...
Roux-en-Y gastric bypass (RYGB) surgery induces various metabolic benefits in severely obese (BMI>...
BACKGROUND: Roux-en-Y gastric bypass (RYGB) surgery has been shown to induce positive metabolic adap...
Mitochondrial dynamics including mitochondrial fission (e.g., Dynamin-related protein 1 (Drp1) and F...
BACKGROUND: A large body of literature indicates the rapidity with which Roux-en-Y gastric bypass (R...
The Roux-en-Y gastric bypass (RYGB) is highly effective in the remission of obesity and associated d...
Severe obesity and Type 2 Diabetes (T2DM) are worldwide health concerns reaching epidemic proportion...
Skeletal muscle is the site at which highly regulated energetic processes take place as a means of m...
IntroductionRoux-en-Y gastric bypass (RYGB) is an effective treatment for type 2 diabetes mellitus (...
Context: Surgical treatments of obesity have been shown to induce rapid and prolonged improvements i...
Roux-en-Y gastric bypass (RYGB) is an effective method to attain sustained weight loss and diabetes ...
It has been shown that Type 2 diabetic patients who undergo Roux-en-Y Gastric Bypass surgery (RYGB) ...
The skeletal muscle of severely obese individuals (BMI > 40 kg/m²) is characterized by a depressed ...
Aim. Bariatric surgery improves insulin sensitivity and glucose tolerance in obese individuals with ...
Skeletal muscle displays an extensive capacity to adapt to a wide range of metabolic and mechanical ...
Visceral adipose tissue (VAT) is associated with cardiometabolic risk factors and insulin resistance...