Tuberculosis and the immune response in children

Tuberculosis is one of the major killers in the world today and has been described as a “global emergency” by WHO. I n I n d i a t h e r e a r e approximately 1 million new cases every year and 500,000 deaths. Tuberculosis also affects children who get the infection from adults. It is important to study the natural history, clinical manifestations and immunological profile of children in order to diagnose them earlier and treat them effectively