The decision taken by the British people to leave the European Union (EU) took many people by surprise. The macro economic, political and social implications are still unclear, but as negotiations begin the post-Brexit world is beginning to take shape. In this article I will argue that Brexit has a number of implications for those involved in career education and guidance. It will explore how the development of the EU since Maastricht has resulted in substantial shifts in the opportunity structure. Out of these changes there have been both winners and losers. Within this context Brexit can be seen as a consequence of the failure of the neoliberal approach taken by the EU to guarantee career development for all. The paper goes on to explore ...