The aim of the study was to evaluate the effect of systematic agitation, increasing ionic strength and gel strength on drug release from a gel-forming matrix (HPMC E10M, E4M and E50LV) using USP type III Bio-Dis apparatus with theophylline as a model drug. The triboelectric charging; particle sizing, water content, true density and SEM of all the hypromellose grades, theophylline and formulated blends were characterised. The results showed that balanced inter-particulate forces exist between drug particles and the excipient surface and this enabled optimum charge to mass ratio to be measured. Agitation and ionic strength affected drug release from E50LV and E4M tablet matrices in comparison to the E10M tablet matrices. Drug release increase...
ABSTRACT: The effects of plastic, hydrophilic and hydrophobic types of polymers and impact of granul...
Design of systems for oral controlled release of drug could take advantages from the knowledge of wh...
The purpose of this study was to develop an extended-release (ER) matrix tablet that shows robust di...
The aim of the study was to evaluate the effect of systematic agitation, increasing ionic strength a...
Theophylline extended release (ER) matrices containing hypromellose (hydroxypropyl methylcellulose (...
Theophylline extended release (ER) matrices containing hypromellose (hydroxypropyl methylcellulose (...
Theophylline extended release (ER) matrices containing hypromellose (hydroxypropyl methylcellulose (...
The objectives of this study were to evaluate the effects of different media ionic concentration str...
The evaluations of the systematic effects of agitation and ionic strength and its impact on tablet c...
The objectives of this study were to evaluate the effects of different media ionic concentration str...
In this article, the influence of agitation in descending and ascending sequences as a systematic me...
The purposes of this work were: (1) to comparatively evaluate the effects of hypromellose viscosity ...
The evaluation of the effects of different media ionic strengths and pH on the release of hydrochlor...
The objectives of the present study are to develop novel sustained release matrix tablets of theophy...
WOS: 000392938000006The objectives of the present study are to develop novel sustained release matri...
ABSTRACT: The effects of plastic, hydrophilic and hydrophobic types of polymers and impact of granul...
Design of systems for oral controlled release of drug could take advantages from the knowledge of wh...
The purpose of this study was to develop an extended-release (ER) matrix tablet that shows robust di...
The aim of the study was to evaluate the effect of systematic agitation, increasing ionic strength a...
Theophylline extended release (ER) matrices containing hypromellose (hydroxypropyl methylcellulose (...
Theophylline extended release (ER) matrices containing hypromellose (hydroxypropyl methylcellulose (...
Theophylline extended release (ER) matrices containing hypromellose (hydroxypropyl methylcellulose (...
The objectives of this study were to evaluate the effects of different media ionic concentration str...
The evaluations of the systematic effects of agitation and ionic strength and its impact on tablet c...
The objectives of this study were to evaluate the effects of different media ionic concentration str...
In this article, the influence of agitation in descending and ascending sequences as a systematic me...
The purposes of this work were: (1) to comparatively evaluate the effects of hypromellose viscosity ...
The evaluation of the effects of different media ionic strengths and pH on the release of hydrochlor...
The objectives of the present study are to develop novel sustained release matrix tablets of theophy...
WOS: 000392938000006The objectives of the present study are to develop novel sustained release matri...
ABSTRACT: The effects of plastic, hydrophilic and hydrophobic types of polymers and impact of granul...
Design of systems for oral controlled release of drug could take advantages from the knowledge of wh...
The purpose of this study was to develop an extended-release (ER) matrix tablet that shows robust di...